The mechanisms that link a transient neural activity to the corresponding increase of
cerebral blood flow (CBF) are termed neurovascular coupling (NVC). They are possibly …

In this article, we describe the mathematical framework of the computational model at the
core of the tool The Virtual Brain (TVB), designed to simulate collective whole brain …

Brain function is thought to emerge from the interactions among neuronal populations. Apart
from traditional efforts to reproduce brain dynamics from the micro-to macroscopic scales …

Neural field theory of the corticothalamic system is applied to predict and analyze the activity
eigenmodes of the bihemispheric brain, focusing particularly on their spatial structure. The …

Studies that validate statistical methods for functional magnetic resonance imaging (fMRI)
data often use simulated data to ensure that the ground truth is known. However, simulated …

Biological phenomena arise through interactions between an organism's intrinsic dynamics
and stochastic forces—random fluctuations due to external inputs, thermal energy, or other …

Abstract A brief (< 4 s) period of neural activation evokes a stereotypical sequence of
vascular and metabolic events to create the hemodynamic response function (HRF) …

Functional MRI (fMRI) experiments rely on precise characterization of the blood oxygen level
dependent (BOLD) signal. As the spatial resolution of fMRI reaches the sub-millimeter …

It is shown how to compute effective and functional connection matrices (eCMs and fCMs)
from anatomical CMs (aCMs) and corresponding strength-of-connection matrices (sCMs) …

Large-scale dynamics of the brain are routinely modelled using systems of nonlinear
dynamical equations that describe the evolution of population-level activity, with distinct …