Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Photodynamic therapy (PDT) has achieved great success in cancer treatment. Despite its
great promise, the efficacy of photodynamic immunotherapy can be limited by the hypoxia in …

Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …

Abstract Service life and range of polymer materials is heavily reliant on their elasticity and
mechanical stability under long‐term loading. Slippage of chain segments under load leads …

The intelligent responsive drug delivery system has great application potential in cancer
precision therapy. Although many antitumor methods have been developed based on drug …

The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

Surgical resection is the first-line therapy for breast cancer. However, residual tumor cells
and the highly immunosuppressive tumor microenvironment (TME) continue to have a …

Traditional hydrogel design and optimization methods usually rely on repeated experiments,
which is time-consuming and expensive, resulting in a slow-moving of advanced hydrogel …

Although immunotherapy has revolutionized oncotherapy, only≈ 15% of head and neck
squamous cell carcinoma (HNSCC) patients benefit from the current therapies. An …