To understand brain function, it is essential that we discover how cellular signaling specifies
normal and pathological brain function. In this regard, chemogenetic technologies represent …

Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …

Despite its increasing use in experimental and clinical settings, the cellular and molecular
mechanisms underlying transcranial direct current stimulation (tDCS) remain unknown …

The contribution of nerves to the pathogenesis of malignancies has emerged as an
important component of the tumour microenvironment. Recent studies have shown that …

Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

Hubel and Wiesel began the modern study of development and plasticity of primary visual
cortex (V1), discovering response properties of cortical neurons that distinguished them from …

Rapid and reversible methods for perturbing the function of specific proteins are desirable
tools for probing complex biological systems. We have developed a general technique to …

Brain‐derived neurotrophic factor (BDNF) is a prototypic neurotrophin that regulates diverse
developmental events from the selection of neural progenitors to the terminal dendritic …

Elucidating the roles of neuronal cell types for physiology and behavior is essential for
understanding brain functions. Perturbation of neuron electrical activity can be used to probe …

Brain-derived neurotrophic factor (BDNF), a cognate ligand for the tyrosine kinase receptor
B (TrkB) receptor, mediates neuronal survival, differentiation, synaptic plasticity, and …