Role of insulin in health and disease: an update

MS Rahman, KS Hossain, S Das, S Kundu… - International journal of …, 2021‏ - mdpi.com
Insulin is a polypeptide hormone mainly secreted by β cells in the islets of Langerhans of the
pancreas. The hormone potentially coordinates with glucagon to modulate blood glucose …

Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021‏ - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020‏ - academic.oup.com
Background Psoriasis is a chronic, systemic immune‐mediated disease characterized by
development of erythematous, indurated, scaly, pruritic and often painful skin plaques …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020‏ - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

Psoriasis and comorbid diseases: epidemiology

J Takeshita, S Grewal, SM Langan, NN Mehta… - Journal of the American …, 2017‏ - Elsevier
Psoriasis is a common chronic inflammatory disease of the skin that is increasingly being
recognized as a systemic inflammatory disorder. Psoriatic arthritis is a well-known …

Gut–skin axis: Unravelling the connection between the gut microbiome and psoriasis

AYK Thye, YR Bah, JWF Law, LTH Tan, YW He… - Biomedicines, 2022‏ - mdpi.com
Evidence has shown that gut microbiome plays a role in modulating the development of
diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The …

The immunogenetics of psoriasis: a comprehensive review

JL Harden, JG Krueger, AM Bowcock - Journal of autoimmunity, 2015‏ - Elsevier
Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology
involving genetic risk factors and environmental triggers. Here we describe the many known …

Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?

E Guttman-Yassky, JG Krueger - Current opinion in immunology, 2017‏ - Elsevier
Psoriasis and atopic dermatitis (AD) are common T-cell mediated inflammatory diseases of
the skin that can be treated by specific cytokine antagonists or more broad …

Immunology of psoriasis

MA Lowes, M Suarez-Farinas… - Annual review of …, 2014‏ - annualreviews.org
The skin is the front line of defense against insult and injury and contains many epidermal
and immune elements that comprise the skin-associated lymphoid tissue (SALT). The …

Scanning the immunopathogenesis of psoriasis

A Chiricozzi, P Romanelli, E Volpe… - International journal of …, 2018‏ - mdpi.com
Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …