Cell-laden hydrogels for osteochondral and cartilage tissue engineering
Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …
challenging to repair the osteochondral interface and full-thickness articular cartilage …
Unlike bone, cartilage regeneration remains elusive
Articular cartilage was predicted to be one of the first tissues to successfully be regenerated,
but this proved incorrect. In contrast, bone (but also vasculature and cardiac tissues) has …
but this proved incorrect. In contrast, bone (but also vasculature and cardiac tissues) has …
Hydrogels for the repair of articular cartilage defects
The repair of articular cartilage defects remains a significant challenge in orthopedic
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …
3D spatiotemporal mechanical microenvironment: a hydrogel‐based platform for guiding stem cell fate
Y Ma, M Lin, G Huang, Y Li, S Wang, G Bai… - Advanced …, 2018 - Wiley Online Library
Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …
Manipulation of stem cells fates: the master and multifaceted roles of biophysical cues of biomaterials
X Wan, Z Liu, L Li - Advanced Functional Materials, 2021 - Wiley Online Library
Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …
injured tissues, making them a promising source of seed cells for tissue engineering. The …
[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …
Tissue engineering of functional articular cartilage: the current status
Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …
Progress in biomechanical stimuli on the cell-encapsulated hydrogels for cartilage tissue regeneration
Background Worldwide, many people suffer from knee injuries and articular cartilage
damage every year, which causes pain and reduces productivity, life quality, and daily …
damage every year, which causes pain and reduces productivity, life quality, and daily …
Dynamic mechanical compression of chondrocytes for tissue engineering: a critical review
DE Anderson, B Johnstone - Frontiers in bioengineering and …, 2017 - frontiersin.org
Articular cartilage functions to transmit and translate loads. In a classical structure–function
relationship, the tissue resides in a dynamic mechanical environment that drives the …
relationship, the tissue resides in a dynamic mechanical environment that drives the …
A guide for using mechanical stimulation to enhance tissue-engineered articular cartilage properties
The use of tissue-engineered articular cartilage (TEAC) constructs has the potential to
become a powerful treatment option for cartilage lesions resulting from trauma or early …
become a powerful treatment option for cartilage lesions resulting from trauma or early …