Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy

S Peng, F **ao, M Chen, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Vaccine-like nanomedicine for cancer immunotherapy

Y Yi, M Yu, W Li, D Zhu, L Mei, M Ou - Journal of Controlled Release, 2023 - Elsevier
The successful clinical application of immune checkpoint blockade (ICB) and chimeric
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Checkpoint nano‐PROTACs for activatable cancer photo‐immunotherapy

C Zhang, M Xu, S He, J Huang, C Xu… - Advanced Materials, 2023 - Wiley Online Library
Checkpoint immunotherapy holds great potential to treat malignancies via blocking the
immunosuppressive signaling pathways, which however suffers from inefficiency and off …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Cell microparticles loaded with tumor antigen and resiquimod reprogram tumor-associated macrophages and promote stem-like CD8+ T cells to boost anti-PD-1 …

X Zhang, Z Wei, T Yong, S Li, N Bie, J Li, X Li… - Nature …, 2023 - nature.com
The durable response rate to immune checkpoint blockade such as anti-programmed cell
death-1 (PD-1) antibody remains relatively low in hepatocellular carcinoma (HCC), mainly …

Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

X Liu, Y Zhuang, W Huang, Z Wu, Y Chen… - Nature …, 2023 - nature.com
The response rate of pancreatic cancer to chemotherapy or immunotherapy pancreatic
cancer is low. Although minimally invasive irreversible electroporation (IRE) ablation is a …