Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …
profoundly revolutionized oncology, whereas low patient response rates and potential …
Vaccine-like nanomedicine for cancer immunotherapy
Y Yi, M Yu, W Li, D Zhu, L Mei, M Ou - Journal of Controlled Release, 2023 - Elsevier
The successful clinical application of immune checkpoint blockade (ICB) and chimeric
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …
Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments
M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …
infections. This treatment dates back to 1900 when a German medical school graduate …
Biomedical polymers: synthesis, properties, and applications
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
Materials engineering strategies for cancer vaccine adjuvant development
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
Checkpoint nano‐PROTACs for activatable cancer photo‐immunotherapy
Checkpoint immunotherapy holds great potential to treat malignancies via blocking the
immunosuppressive signaling pathways, which however suffers from inefficiency and off …
immunosuppressive signaling pathways, which however suffers from inefficiency and off …
Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
Cell microparticles loaded with tumor antigen and resiquimod reprogram tumor-associated macrophages and promote stem-like CD8+ T cells to boost anti-PD-1 …
X Zhang, Z Wei, T Yong, S Li, N Bie, J Li, X Li… - Nature …, 2023 - nature.com
The durable response rate to immune checkpoint blockade such as anti-programmed cell
death-1 (PD-1) antibody remains relatively low in hepatocellular carcinoma (HCC), mainly …
death-1 (PD-1) antibody remains relatively low in hepatocellular carcinoma (HCC), mainly …
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy
X Liu, Y Zhuang, W Huang, Z Wu, Y Chen… - Nature …, 2023 - nature.com
The response rate of pancreatic cancer to chemotherapy or immunotherapy pancreatic
cancer is low. Although minimally invasive irreversible electroporation (IRE) ablation is a …
cancer is low. Although minimally invasive irreversible electroporation (IRE) ablation is a …