Acetamides: chemotherapeutic agents for inflammation-associated cancers

P Rani, D Pal, RR Hegde, SR Hashim - Journal of Chemotherapy, 2016 - Taylor & Francis
Now clear evidences are available to support the hypothesis that inflammation accelerates
the conditions including events and molecules that reach to various types of cancers …

Novel 1, 2, 4‐triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies

A Turky, FF Sherbiny, AH Bayoumi… - Archiv der …, 2020 - Wiley Online Library
Abstract Three novel series of 1, 2, 4‐triazole derivatives were designed and synthesized as
potential adenosine A2B receptor antagonists. The design of the new compounds depended …

[HTML][HTML] N-Phenyl-2-p-tolylthiazole-4-carboxamide derivatives: Synthesis and cytotoxicity evaluation as anticancer agents

A Mohammadi-Farani, A Foroumadi… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
Objective (s): According to the prevalence of neoplastic diseases, there is a deep necessity
for discovery of novel anticancer drugs in the field of medicinal chemistry. In the current …

[HTML][HTML] N-(5-Mercapto-1, 3, 4-thiadiazol-2-yl)-2-phenylacetamide derivatives: synthesis and in-vitro cytotoxicity evaluation as potential anticancer agents

A Mohammadi-Farani, N Heidarian… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
A new series of N-(5-Mercapto-1, 3, 4-thiadiazol-2-yl)-2-phenylacetamide derivatives (3a-3j)
were synthesized via an amidation reaction using EDC and HOBt in acetonitrile solvent at …

Synthesis and evaluation of anticonvulsant activity of (Z)-4-(2-oxoindolin-3-ylideneamino)-N-phenylbenzamide derivatives in mice

MR Khajouei, A Mohammadi-Farani… - Research in …, 2018 - journals.lww.com
Due to resistance of some epileptic patients to the current medications and the general
incidence of severe side effects of these drugs, development and discovery of novel …

Phytoconstituents from Curcuma longa L. aqueous ethanol extract and its immunomodulatory effect on diabetic infected rats

MH Shabana, EM Shahy, MM Taha… - Egyptian …, 2015 - journals.lww.com
Materials and methods The extraction and isolation of the constituents of C. longa were
performed according to the standard methods of column, paper, and thin-layer …

Biophysical investigation and antitumor potential of heterocyclic palladium-based agent: cytotoxicity, spectroscopic and molecular docking approaches in interaction …

M Saeidifar, R Sabbaghzadeh… - Polycyclic Aromatic …, 2021 - Taylor & Francis
With the aim of cancer treatment, interaction between 1-hexyldithiocarbamato 1, 10-
phenanthrolinepalladium (II) nitrate complex ([Pd (Hex-Dtc)(Phen)] NO3, Pd-HDP), as a …

[HTML][HTML] Synthesis and Biological Evaluation of N-(5-(pyridin-2-yl)-1, 3, 4-thiadiazol-2-yl) benzamide Derivatives as Lipoxygenase Inhibitor with Potential Anticancer …

A Aliabadi, A Mohammadi-Farani… - Iranian Journal of …, 2017 - ncbi.nlm.nih.gov
In the recent years, the role of LOX enzymes in the origin of neoplastic diseases such as
colorectal, skin, pancreatic and renal cancers has been confirmed. A new series of 1, 3, 4 …

[PDF][PDF] 4-Halo-N-(5-(trifluoromethyl)-1, 3, 4-thiadiazol-2-yl) benzamide and Benzothioamide Derivatives: Synthesis and in vitro Anticancer Assessment

AR Aliabadi, H Harasami Neek, Y Bahmani - Iranian Journal of Chemistry …, 2020 - ijcce.ac.ir
Cancer is a lethal disorder that has caused a serious threat to human health and nowadays
there is a crucial need for the development of novel anticancer agents. A new series of 1, 3 …

Synthesis and acetylcholinesterase inhibitory assessment of benzamide derivatives incorporated piperazine moiety as potential anti-Alzheimer agents

A Aliabadi, A Mohammadi-Farani… - Journal of …, 2017 - search.proquest.com
According to the obtained information from X-ray crystallography, it has been characterized
that two distinct parts are observable in the active site of AChE.[...] the ethylacetate was …