Simple Summary The ability to predict or detect colorectal cancer (CRC) recurrence early
after surgery enables physicians to apply appropriate treatment plans and different follow-up …

Simple Summary Total neoadjuvant therapy is a strategy developed to improve the efficacy
of chemotherapy in locally advanced rectal cancer by anticipating all the chemotherapy …

(ASCRS) is dedicated to ensuring high-quality patient care by advancing the science,
prevention, and management of disorders and diseases of the colon, rectum, and anus. The …

Simple Summary Worldwide there is still unwarranted variation in peri-operative
management and subsequently oncological outcome following pelvic exenteration for …

Colorectal carcinoma is the second leading cause of cancer-related deaths, and indeed,
rectal cancer accounting for approximately one third of newly diagnosed patients. Gold …

Background Neoadjuvant therapy can lead to different tumor regression grades (TRG) in
rectal cancer after neoadjuvant therapy. The purposes of this study are to investigate the …

Purpose The standard of care for locally advanced rectal cancer (LARC) has changed from
a single radical surgical treatment to the current multimodality treatment (standard …

Objective: To evaluate the impact of neoadjuvant multi-agent systemic chemotherapy and
radiation (TNT) vs neoadjuvant single-agent chemoradiation (nCRT) and multi-agent …

Introduction Total neoadjuvant therapy (TNT) is a new therapeutic strategy in patients with
rectal cancer. We examined the role of TNT, in addition to other pre-operative factors, as a …

Introduction Historically, multimodal therapeutic strategies involving preoperative
chemoradiotherapy (CRT), surgery, and adjuvant chemotherapy (CT) have been employed …