Infections, inflammation and epilepsy
Epilepsy is the tendency to have unprovoked epileptic seizures. Anything causing structural
or functional derangement of brain physiology may lead to seizures, and different conditions …
or functional derangement of brain physiology may lead to seizures, and different conditions …
The impact of microglial activation on blood-brain barrier in brain diseases
ACC da Fonseca, D Matias, C Garcia… - Frontiers in cellular …, 2014 - frontiersin.org
The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells (ECs)
together with neurons and glial cells, including microglia, forms the neurovascular unit …
together with neurons and glial cells, including microglia, forms the neurovascular unit …
Animal models of epilepsy: use and limitations
L Kandratavicius, PA Balista… - Neuropsychiatric …, 2014 - Taylor & Francis
Epilepsy is a chronic neurological condition characterized by recurrent seizures that affects
millions of people worldwide. Comprehension of the complex mechanisms underlying …
millions of people worldwide. Comprehension of the complex mechanisms underlying …
Glia and epilepsy: excitability and inflammation
Epilepsy is characterized by recurrent spontaneous seizures due to hyperexcitability and
hypersynchrony of brain neurons. Current theories of pathophysiology stress neuronal …
hypersynchrony of brain neurons. Current theories of pathophysiology stress neuronal …
The role of inflammation in epilepsy
Epilepsy is the third most common chronic brain disorder, and is characterized by an
enduring predisposition to generate seizures. Despite progress in pharmacological and …
enduring predisposition to generate seizures. Despite progress in pharmacological and …
The kainic acid models of temporal lobe epilepsy
Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …
Cytokines in new‐onset refractory status epilepticus predict outcomes
Objective The objective of this study was to investigate inflammation using cerebrospinal
fluid (CSF) and serum cytokines/chemokines in patients with new‐onset refractory status …
fluid (CSF) and serum cytokines/chemokines in patients with new‐onset refractory status …
Inflammation in epileptogenesis after traumatic brain injury
Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
Autoimmune seizures and epilepsy
C Geis, J Planagumà, M Carreño… - The Journal of …, 2019 - Am Soc Clin Investig
The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …
Inflammation and reactive oxygen species as disease modifiers in epilepsy
G Terrone, S Balosso, A Pauletti, T Ravizza… - …, 2020 - Elsevier
Neuroinflammation and reactive oxygen and nitrogen species are rapidly induced in the
brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …
brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …