Microorganisms have the capacity to utilize a variety of nutrients and adapt to continuously
changing environmental conditions. Many microorganisms, including yeast and bacteria …

Glycogen and trehalose are the two glucose stores of yeast cells. The large variations in the
cell content of these two compounds in response to different environmental changes …

Global quantitative analysis of genetic interactions is a powerful approach for deciphering
the roles of genes and map** functional relationships among pathways. Using colony size …

This review traces the historical origins and conceptual developments leading to the current
state of knowledge of the three superfamilies of protein Ser/Thr phosphatases.'PR …

The dephosphorylation of proteins on serine and threonine residues is a major mechanism
of cellular regulation. Many novel protein serine/threonine phosphatases in the PPP family …

INTRODUCTION Phosphorylation of structural and regulatory proteins is a major
intracellular control mechanism in eukaryotes. The phosphoryl-ation state of a protein is a …

A novel human protein serine/threonine phosphatase, PP5, and a structurally related
phosphatase in Saccharomyces cerevisiae, PPT1, have been identified from their cDNA and …

Since the isolation of the first yeast protein phosphatase genes in 1989, much progress has
been made in understanding this important group of proteins. Yeast contain genes encoding …

Certain mammalian growth modulators, such as tumor necrosis factor alpha, interleukin-
1beta, and gamma-interferon, induce an antiproliferative response-terminal differentiation …

Reversible phospho-dephosphorylation of proteins is a major mechanism for the control of
cellular functions. By large, Ser and Thr are the most frequently residues phosphorylated in …