With the development of modern high-throughput omic measurement platforms, it has
become essential for biomedical studies to undertake an integrative (combined) approach to …

Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …

Tailoring optimal treatment for individual cancer patients remains a significant challenge. To
address this issue, we developed PERCEPTION (PERsonalized Single-Cell Expression …

The number of druggable tumor-specific molecular aberrations has grown substantially in
the past decade, with a significant survival benefit obtained from biomarker matching …

Simple Summary Artificial intelligence (AI) technology has been advancing rapidly in recent
years and is being implemented in society. The medical field is no exception, and the clinical …

Extending the benefits of tumor molecular profiling for all cancer patients requires a
comprehensive analysis of tumor genomes across distinct patient populations worldwide. In …

Motivation Cancer subtypes were usually defined based on molecular characterization of
single omic data. Increasingly, measurements of multiple omic profiles for the same cohort …

Cancer cells can leverage several cell-intrinsic and-extrinsic mechanisms to escape
immune system recognition. The inherent complexity of the tumor microenvironment, with its …

High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

Tumor progression is typically accompanied by an accumulation of driver and passenger
somatic mutations. A handful of those mutations occur in protein coding genes which …