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Astrocyte regulation of synaptic signaling in psychiatric disorders
Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in sha** neuronal synaptic activity and along with the pre-and …
role of astroglia in sha** neuronal synaptic activity and along with the pre-and …
Astrocytes in cocaine addiction and beyond
Drug addiction remains a key biomedical challenge facing current neuroscience research. In
addition to neural mechanisms, the focus of the vast majority of studies to date, astrocytes …
addition to neural mechanisms, the focus of the vast majority of studies to date, astrocytes …
[HTML][HTML] Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are …
Clinical and preclinical studies indicate that adaptations in corticostriatal neurotransmission
significantly contribute to heroin relapse vulnerability. In animal models, heroin self …
significantly contribute to heroin relapse vulnerability. In animal models, heroin self …
Effects of methamphetamine self-administration and extinction on astrocyte structure and function in the nucleus accumbens core
Astrocytes provide support for neurons, regulate metabolic processes, and influence
neuronal communication in a variety of ways, including through the homeostatic regulation …
neuronal communication in a variety of ways, including through the homeostatic regulation …
Interactions of neuroimmune signaling and glutamate plasticity in addiction
Chronic use of drugs of abuse affects neuroimmune signaling; however, there are still many
open questions regarding the interactions between neuroimmune mechanisms and …
open questions regarding the interactions between neuroimmune mechanisms and …
Heroin cue–evoked astrocytic structural plasticity at nucleus accumbens synapses inhibits heroin seeking
Background Opioid addiction is a critical medical and societal problem characterized by
vulnerability to relapse. Glutamatergic synapses in the nucleus accumbens regulate the …
vulnerability to relapse. Glutamatergic synapses in the nucleus accumbens regulate the …
Astrocytes as cellular mediators of cue reactivity in addiction
Highlights•NAcore astrocytes undergo morphological remodeling after addictive drug use
resulting in their reduced synaptic proximity.•Repeated self-administration of …
resulting in their reduced synaptic proximity.•Repeated self-administration of …
Control of complex behavior by astrocytes and microglia
Evidence that glial cells influence behavior has been gaining a steady foothold in scientific
literature. Out of the five main subtypes of glial cells in the brain, astrocytes and microglia …
literature. Out of the five main subtypes of glial cells in the brain, astrocytes and microglia …
Heroin seeking and extinction from seeking activate matrix metalloproteinases at synapses on distinct subpopulations of accumbens cells
Background Seeking addictive drugs is regulated by synaptic plasticity in the nucleus
accumbens core and involves distinct plasticity in D 1 and D 2 receptor–expressing medium …
accumbens core and involves distinct plasticity in D 1 and D 2 receptor–expressing medium …
Stress elicits contrasting effects on the structure and number of astrocytes in the amygdala versus hippocampus
Stress causes divergent patterns of structural and physiological plasticity in the
hippocampus versus amygdala. However, a majority of earlier studies focused primarily on …
hippocampus versus amygdala. However, a majority of earlier studies focused primarily on …