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Microbiome engineering: synthetic biology of plant-associated microbiomes in sustainable agriculture
To support an ever-increasing population, modern agriculture faces numerous challenges
that pose major threats to global food and energy security. Plant-associated microbes, with …
that pose major threats to global food and energy security. Plant-associated microbes, with …
Biohybrid robots: recent progress, challenges, and perspectives
The past ten years have seen the rapid expansion of the field of biohybrid robotics. By
combining engineered, synthetic components with living biological materials, new robotics …
combining engineered, synthetic components with living biological materials, new robotics …
DNA-based communication in populations of synthetic protocells
Develo** molecular communication platforms based on orthogonal communication
channels is a crucial step towards engineering artificial multicellular systems. Here, we …
channels is a crucial step towards engineering artificial multicellular systems. Here, we …
A comprehensive survey of recent advancements in molecular communication
With much advancement in the field of nanotechnology, bioengineering, and synthetic
biology over the past decade, microscales and nanoscales devices are becoming a reality …
biology over the past decade, microscales and nanoscales devices are becoming a reality …
A brief history of synthetic biology
The ability to rationally engineer microorganisms has been a long-envisioned goal dating
back more than a half-century. With the genomics revolution and rise of systems biology in …
back more than a half-century. With the genomics revolution and rise of systems biology in …
Single-cell reconstruction of progression trajectory reveals intervention principles in pathological cardiac hypertrophy
Z Ren, P Yu, D Li, Z Li, Y Liao, Y Wang, B Zhou… - Circulation, 2020 - ahajournals.org
Background: Pressure overload–induced pathological cardiac hypertrophy is a common
predecessor of heart failure, the latter of which remains a major cardiovascular disease with …
predecessor of heart failure, the latter of which remains a major cardiovascular disease with …
Designing cell function: assembly of synthetic gene circuits for cell biology applications
M **e, M Fussenegger - Nature Reviews Molecular Cell Biology, 2018 - nature.com
Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
Metabolic division of labor in microbial systems
Metabolic pathways are often engineered in single microbial populations. However, the
introduction of heterologous circuits into the host can create a substantial metabolic burden …
introduction of heterologous circuits into the host can create a substantial metabolic burden …
Synthetic biology: applications come of age
Synthetic biology is bringing together engineers and biologists to design and build novel
biomolecular components, networks and pathways, and to use these constructs to rewire …
biomolecular components, networks and pathways, and to use these constructs to rewire …
Synthetic circuits integrating logic and memory in living cells
Logic and memory are essential functions of circuits that generate complex, state-dependent
responses. Here we describe a strategy for efficiently assembling synthetic genetic circuits …
responses. Here we describe a strategy for efficiently assembling synthetic genetic circuits …