Once acquired, a fearful memory can persist for a lifetime. Although learned fear can be
extinguished, extinction memories are fragile. The resilience of fear memories to extinction …

Purpose of Review PTSD in youth is common and debilitating. In contrast to adult PTSD,
relatively little is known about the neurobiology of pediatric PTSD, nor how …

Traumatic childhood events are associated with a wide range of negative physical,
psychological and adaptive outcomes over the life course and are one of the few identifiable …

An update to the classic text that links neuroscience and human behavior in the context of
therapy. This groundbreaking book explores the recent revolution in psychotherapy that has …

The last decade of neuroimaging research has yielded important information concerning the
structure, neurochemistry, and function of the amygdala, medial prefrontal cortex, and …

The prevailing neurocircuitry models of anxiety disorders have been amygdalocentric in
form. The bases for such models have progressed from theoretical considerations …

How do people effectively regulate their emotional reactions? Why are some people better
at this than others? Most prior research has addressed these questions by focusing on …

Background Previous functional neuroimaging studies have demonstrated exaggerated
amygdala responses and diminished medial prefrontal cortex responses during the …

Nightmares are common, occurring weekly in 4%-10% of the population, and are associated
with female gender, younger age, increased stress, psychopathology, and dispositional …

Background: A central problem in posttraumatic stress disorder (PTSD) is a reduced
capacity to suppress fear under safe conditions. Previously, we have shown that combat …