Oxidative stress is important in the pathophysiology of obesity, altering regulatory factors of
mitochondrial activity, modifying the concentration of inflammation mediators associated with …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Sirtuins are class III histone deacetylases, whose enzymatic activity is dependent on NAD+
as a cofactor. Sirtuins are reported to modulate numerous activities by controlling gene …

Stilbenes are some of the important phenolic compounds originating from plant families like
Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6 …

Wine consumption has been popular worldwide for many centuries. Based on in vitro and in
vivo studies, a certain amount of everyday wine consumption may prevent various chronic …

Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

Dietary habits such as caloric restriction or nutrients that mimic these effects may exert
beneficial effects on brain aging. The plant-derived polyphenol resveratrol has been shown …

Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

Cardiovascular disease (CVD) is the main cause of death globally and responsible for the
second highest number of deaths in Canada. Medical advancements in the treatment of …

Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …