[HTML][HTML] New antimicrobial strategies based on metal complexes

M Claudel, JV Schwarte, KM Fromm - Chemistry, 2020 - mdpi.com
Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

Quinoxaline, its derivatives and applications: A State of the Art review

JA Pereira, AM Pessoa, MNDS Cordeiro… - European Journal of …, 2015 - Elsevier
Quinoxaline derivatives are an important class of heterocycle compounds, where N replaces
some carbon atoms in the ring of naphthalene. Its molecular formula is C 8 H 6 N 2, formed …

Quinoxaline: An insight into the recent pharmacological advances

S Tariq, K Somakala, M Amir - European Journal of Medicinal Chemistry, 2018 - Elsevier
Quinoxaline, a fused heterocycle of benzene and pyrazine rings has gained considerable
attention in the field of contemporary medicinal chemistry. The moiety is of substantial …

Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological …

YA Ammar, AA Farag, AM Ali, SA Hessein, AA Askar… - Bioorganic …, 2020 - Elsevier
Abstract A series of thiadiazino [5, 6-b] quinoxaline and thiazolo [4, 5-b] quinoxaline
derivatives was designed and synthetized from the reaction of 2, 3-dichloro-6 …

Hydrazides/hydrazones as antimicrobial and anticancer agents in the new millennium

P Kumar, B Narasimhan - Mini reviews in medicinal chemistry, 2013 - benthamdirect.com
Hydrazide/hydrazone derivatives are of quite interest for medicinal chemists because of their
vast spectrum of biological activity. Literature reports reveal that the hydrazide derivatives …

Synthesis of some new 2-(3-methyl-7-substituted-2-oxoquinoxalinyl)-5-(aryl)-1, 3, 4-oxadiazoles as potential non-steroidal anti-inflammatory and analgesic agents

S Wagle, AV Adhikari, NS Kumari - 2008 - nopr.niscpr.res.in
Ethyl (3-methyl-7-substituted-2-oxoquinoxalin-1 (2H)-yl) acetates 2a-c are prepared by the
condensation of ethyl chloroacetate with 3-methyl-7-substituted quinoxalin-2 (1H)-ones 1a …

Exploring quinoxaline derivatives: An overview of a new approach to combat antimicrobial resistance

H Khatoon, SMM Faudzi - European journal of medicinal chemistry, 2024 - Elsevier
Antimicrobial resistance (AMR) has emerged as a long-standing global issue ever since the
introduction of penicillin, the first antibiotic. Scientists are constantly working to develop …

Investigation of indole functionalized pyrazoles and oxadiazoles as anti-inflammatory agents: Synthesis, in-vivo, in-vitro and in-silico analysis

D Kumar, RR Kumar, S Pathania, PK Singh, S Kalra… - Bioorganic …, 2021 - Elsevier
There are several potential side and adverse effects are found to be associated with the anti-
inflammatory drugs in clinical practice. The long-term use of these clinical agents highly …

Synthesis, crystal structures, and biological evaluation of Cu (II) and Zn (II) complexes of 2-benzoylpyridine Schiff bases derived from S-methyl-and S …

MX Li, LZ Zhang, CL Chen, JY Niu, BS Ji - Journal of inorganic biochemistry, 2012 - Elsevier
Two NNS tridentate Schiff base ligands of 2-benzoylpyridine S-methyldithiocarbazate (HL1)
and 2-benzoylpyridine S-phenyldithiocarbazate (HL2) and their transition metal complexes …

Antimicrobial agents based on metal complexes: present situation and future prospects

B Sharma, S Shukla, R Rattan, M Fatima… - International Journal …, 2022 - Wiley Online Library
The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore,
a dire need to explore new antimicrobial entities that can combat against the increasing …