Organic reactions in microdroplets: Reaction acceleration revealed by mass spectrometry

X Yan, RM Bain, RG Cooks - … Chemie International Edition, 2016 - Wiley Online Library
The striking finding that reaction acceleration occurs in confined‐volume solutions sets up
an apparent conundrum: Microdroplets formed by spray ionization can be used to monitor …

Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis

RL Hartman, JP McMullen… - Angewandte Chemie …, 2011 - Wiley Online Library
The fine chemicals and pharmaceutical industries are transforming how their products are
manufactured, where economically favorable, from traditional batchwise processes to …

Droplet microfluidics—A tool for single‐cell analysis

HN Joensson… - Angewandte Chemie …, 2012 - Wiley Online Library
Droplet microfluidics allows the isolation of single cells and reagents in monodisperse
picoliter liquid capsules and manipulations at a throughput of thousands of droplets per …

Synthesis, functionalization, and design of magnetic nanoparticles for theranostic applications

J Mosayebi, M Kiyasatfar… - Advanced Healthcare …, 2017 - Wiley Online Library
In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs)
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …

Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

AB Theberge, F Courtois, Y Schaerli… - Angewandte Chemie …, 2010 - Wiley Online Library
Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …

Droplet and fluid gating by biomimetic Janus membranes

X Tian, H **, J Sainio, RHA Ras… - Advanced Functional …, 2014 - Wiley Online Library
The ability to gate (ie, allow or block) droplet and fluid transport in a directional manner
represents an important form of liquid manipulation and has tremendous application …

Green and sustainable chemical synthesis using flow microreactors

J Yoshida, H Kim, A Nagaki - ChemSusChem, 2011 - Wiley Online Library
Several features that allow flow microreactors contribute to green and sustainable chemical
synthesis are presented:(1) For extremely fast reactions, kinetics often cannot be used …

High throughput strategies for the discovery and optimization of catalytic reactions

ES Isbrandt, RJ Sullivan… - Angewandte Chemie …, 2019 - Wiley Online Library
Homogeneous catalysis has provided chemists with numerous transformations to enable
rapid construction of organic molecules. However, these reactions are complex, requiring …

Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability

JQ Boedicker, ME Vincent… - … Chemie (International ed …, 2009 - pmc.ncbi.nlm.nih.gov
Herein we show that upon confinement in small volumes, groups of Pseudomonas
aeruginosa bacteria, containing as few as one to three cells, are able to initiate quorum …

Droplet‐based microreactors for the synthesis of magnetic iron oxide nanoparticles

L Frenz, A El Harrak, M Pauly… - Angewandte Chemie …, 2008 - Wiley Online Library
Microfluidic systems are a powerful tool to study and optimize a wide range of biological and
chemical reactions,[1] and their use for the synthesis of nanoparticles is attracting more and …