Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder …

Glucocorticoids are essential steroid hormones secreted from the adrenal gland in response
to stress. Since their discovery in the 1940s, glucocorticoids have been widely prescribed to …

Progress in our understanding of the role of the maternal immune system during healthy
pregnancy will help us better understand the role of the immune system in adverse …

The central nervous system (CNS) regulates innate immune responses through hormonal
and neuronal routes. The neuroendocrine stress response and the sympathetic and …

The airway epithelium represents the first point of contact for inhaled foreign organisms. The
protective arsenal of the airway epithelium is provided in the form of physical barriers and a …

Thymic stromal lymphopoietin (TSLP) is elevated in asthma and triggers dendritic cell-
mediated activation of Th2 inflammatory responses. Although TSLP has been shown to be …

It has become increasingly clear that airway epithelial cells are central participants in innate
and adaptive immune responses as well as mucosal inflammation. Epithelial cells produce …

In mammals, molecular circadian clocks are present in most cells of the body, and this
circadian network plays an important role in synchronizing physiological processes and …

Preterm birth is the major cause of neonatal mortality and morbidity, and bacterial infections
that ascend from the lower female reproductive tract are the most common route of uterine …

Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …