Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Cell-based scaffold-free therapies seek to develop in vitro organotypic three-dimensional
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …

Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …

In vivo, the interior and exterior of cells is populated by various macromolecules that create
an extremely crowded milieu. Yet again, in vitro eukaryotic cell culture is conducted in dilute …

Bone defects caused by trauma, tumour resection, infection and congenital deformities,
together with articular cartilage defects and cartilage–subchondral bone complex defects …

Hydrogels with on‐demand tunable mechanical properties within sensitive biological
environments are of critical importance for examining cellular responses to cell culture …

Tissue engineering has attracted significant attention since the 1980s, and the applications
of tissue engineering have been expanding. To produce a cell-dense tissue, cell sheet …

Cell sheet engineering, a scaffold-free tissue fabrication technique, has proven to be an
important breakthrough technology in regenerative medicine. Over the past two decades …

Background The periosteum plays a crucial role in the development and injury healing
process of bone. The purpose of this study was to construct a biomimetic periosteum with a …

Utilizing tissue-specific extracellular matrices (ECMs) is vital for replicating the composition
of native tissues and develo** biologically relevant biomaterials. Human-or animal …