The action potential of the squid giant axon is formed by just two voltage-dependent
conductances in the cell membrane, yet mammalian central neurons typically express more …

To fire at high rates, neurons express ionic currents that work together to minimize refractory
periods by ensuring that sodium channels are available for activation shortly after each …

Sensory stimuli typically activate many receptors at once and therefore should lead to
increases in correlated activity among central neurons. Such correlated activity could be a …

The electric fish Apteronotus leptorhynchus emits a high‐frequency electric organ discharge
(EOD) sensed by specialized electroreceptors (P‐units) distributed across the fish's skin …

Sensory signals of widely differing dynamic range and intensity are transformed into a
common firing rate code by thalamocortical neurons. While a great deal is known about the …

The GABA projection neurons in the substantial nigra pars reticulata (SNr) are key output
neurons of the basal ganglia motor control circuit. These neurons fire sustained high …

The tuning of neuronal responsiveness to specific stimulus frequencies is an important
computation across many sensory modalities. The weakly electric fish Apteronotus …

Many central neurons support active dendritic spike backpropagation mediated by voltage-
gated currents. Active spikes in dendrites have been shown capable of providing feedback …

The functional role of cholinergic input in the modulation of sensory responses was studied
using a combination of in vivo and in vitro electrophysiology supplemented by mathematical …

Pyramidal neurons of the electrosensory lateral line lobe (ELL) of Apteronotus
leptorhynchus express Kv3-type voltage-gated potassium channels that give rise to high …