Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake

I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …

Tumor-derived exosomes: the next generation of promising cell-free vaccines in cancer immunotherapy

M Naseri, M Bozorgmehr, M Zöller… - …, 2020 - Taylor & Francis
Identification of immunogenic tumor antigens that are efficiently processed and delivered by
dendritic cells to prime the immune system and to induce an appropriate immune response …

Single-vesicle assays using liposomes and cell-derived vesicles: from modeling complex membrane processes to synthetic biology and biomedical applications

H Pick, AC Alves, H Vogel - Chemical reviews, 2018 - ACS Publications
The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

TLR4 participates in the transmission of ethanol-induced neuroinflammation via astrocyte-derived extracellular vesicles

F Ibáñez, J Montesinos, JR Ureña-Peralta… - Journal of …, 2019 - Springer
Background Current evidence indicates that extracellular vesicles (EVs) participate in
intercellular signaling, and in the regulation and amplification of neuroinflammation. We …

Ceramide and exosomes: a novel target in cancer biology and therapy

A Elsherbini, E Bieberich - Advances in Cancer Research, 2018 - Elsevier
Exosomes are secreted extracellular vesicles (EVs) that carry micro RNAs and other factors
to reprogram cancer cells and tissues affected by cancer. Exosomes are exchanged …

Cancer‐derived non‐coding RNAs endow tumor microenvironment with immunosuppressive properties

T Hu, R Shi, Y Gu, H Zhou, Y Fang, T Xu… - Wiley …, 2024 - Wiley Online Library
Non‐coding RNAs (ncRNAs) have attracted extensive attention due to their vital roles in
tumorigenesis and progression, especially in the immunotherapy resistance. Tumor …

Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins

T Hikita, M Miyata, R Watanabe, C Oneyama - Scientific reports, 2018 - nature.com
Exosomes have emerged as important mediators of intercellular communication. Although
their modes of action have been elucidated, the molecular mechanisms underlying their …

Selective isolation of liver-derived extracellular vesicles redefines performance of miRNA biomarkers for non-alcoholic fatty liver disease

LA Newman, Z Useckaite, J Johnson, MJ Sorich… - Biomedicines, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease.
Definitive diagnosis of the progressive form, non-alcoholic steatohepatitis (NASH), requires …

[HTML][HTML] Extracellular vesicles and Alzheimer's disease in the novel era of Precision Medicine: Implications for disease progression, diagnosis and treatment

P Gomes, F Tzouanou, K Skolariki… - Experimental …, 2022 - Elsevier
Extracellular vesicles (EVs), secreted membranous nano-sized particles, are critical
intercellular messengers participating in nervous system homeostasis, while recent …

Spatial and temporal tracking of cardiac exosomes in mouse using a nano-luciferase-CD63 fusion protein

W Luo, Y Dai, Z Chen, X Yue… - Communications …, 2020 - nature.com
Exosomes are secreted extracellular vesicles with lipid bilayer membranes. They are
emerging as a new category of messengers that facilitate cross-talk between cells, tissues …