Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …

Heavy drinking and alcohol use disorder are major public health problems. Practitioners not
specialising in alcohol treatment are often unaware of the guidelines for preventing …

Alcohol use disorders (AUDs) is one of the leading causes of disease and disability in
almost all European countries. Among the alcohol-related diseases, alcoholic liver disease …

Molecular diagnostics, the use of diagnostic testing to understand the molecular
mechanisms of an individual patient's disease, will be pivotal in the delivery of safe and …

Chronic heavy alcohol use impacts all major neurotransmitter systems and is associated
with multiple medical, psychiatric, and social problems. Available evidence‐based …

Addictive disorders are partly heritable, chronic, relapsing conditions that account for a
tremendous disease burden. Currently available addiction pharmacotherapies are only …

Objective Topiramate has been shown to reduce drinking and heavy drinking in individuals
with alcohol dependence whose goal was to stop drinking. The authors evaluated the …

More than 76 million people world‐wide are estimated to have diagnosable alcohol use
disorders (AUDs)(alcohol abuse or dependence), making these disorders a major global …

Excessive alcohol use is the cause of an ongoing public health crisis, and accounts for~ 5%
of global disease burden. A minority of people with recreational alcohol use develop alcohol …