Inertial microfluidic physics

H Amini, W Lee, D Di Carlo - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidics has experienced massive growth in the past two decades, and especially with
advances in rapid prototy** researchers have explored a multitude of channel structures …

Inertial focusing in microfluidics

JM Martel, M Toner - Annual review of biomedical engineering, 2014 - annualreviews.org
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …

Size-selective collection of circulating tumor cells using Vortex technology

E Sollier, DE Go, J Che, DR Gossett, S O'Byrne… - Lab on a Chip, 2014 - pubs.rsc.org
A blood-based, low cost alternative to radiation intensive CT and PET imaging is critically
needed for cancer prognosis and management of its treatment.“Liquid biopsies” of …

Computational inertial microfluidics: a review

SR Bazaz, A Mashhadian, A Ehsani, SC Saha… - Lab on a Chip, 2020 - pubs.rsc.org
Since the discovery of inertial focusing in 1961, numerous theories have been put forward to
explain the migration of particles in inertial flows, but a complete understanding is still …

The lattice Boltzmann method for nearly incompressible flows

P Lallemand, L Luo, M Krafczyk, WA Yong - Journal of Computational …, 2021 - Elsevier
This review summarizes the rigorous mathematical theory behind the lattice Boltzmann
equation (LBE). Relevant properties of the Boltzmann equation and a derivation of the LBE …

Inertio-elastic focusing of bioparticles in microchannels at high throughput

EJ Lim, TJ Ober, JF Edd, SP Desai, D Neal… - Nature …, 2014 - nature.com
Controlled manipulation of particles from very large volumes of fluid at high throughput is
critical for many biomedical, environmental and industrial applications. One promising …

Focusing of sub-micrometer particles in microfluidic devices

T Zhang, ZY Hong, SY Tang, W Li, DW Inglis… - Lab on a Chip, 2020 - pubs.rsc.org
Sub-micrometer particles (0.10–1.0 μm) are of great significance to study, eg, microvesicles
and protein aggregates are targets for therapeutic intervention, and sub-micrometer …

Micro-scale blood plasma separation: from acoustophoresis to egg-beaters

M Kersaudy-Kerhoas, E Sollier - Lab on a Chip, 2013 - pubs.rsc.org
Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating
nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite …

Submicron particle focusing and exosome sorting by wavy microchannel structures within viscoelastic fluids

Y Zhou, Z Ma, M Tayebi, Y Ai - Analytical chemistry, 2019 - ACS Publications
Exosomes, submicron membrane vesicles (30− 200 nm) secreted by almost all cells,
containing significant information such as proteins, microRNAs and DNAs, are closely …

Microfluidics for producing poly (lactic-co-glycolic acid)-based pharmaceutical nanoparticles

X Li, X Jiang - Advanced drug delivery reviews, 2018 - Elsevier
Microfluidic chips allow the rapid production of a library of nanoparticles (NPs) with distinct
properties by changing the precursors and the flow rates, significantly decreasing the time …