Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials
D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …
implants and is a major obstacle to the development of implantable biomaterials and …
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
The heterogeneity of exosomal populations has hindered our understanding of their
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …
Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein AI in corona formation
M Li, X **, T Liu, F Fan, F Gao, S Chai… - Nature communications, 2022 - nature.com
Nanoparticle elasticity is crucial in nanoparticles' physiological fate, but how this occurs is
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
Material stiffness influences the polarization state, function and migration mode of macrophages
Biomaterial implantation is followed by an inflammatory cascade dominated by
macrophages, which determine implant acceptance or rejection through pro-and anti …
macrophages, which determine implant acceptance or rejection through pro-and anti …
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …
administration into the body. This results in reduced delivery to the targeted diseased tissue …
Polymeric particle-based therapies for acute inflammatory diseases
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …
[HTML][HTML] Influencing factors and strategies of enhancing nanoparticles into tumors in vivo
M Zhang, S Gao, D Yang, Y Fang, X Lin, X **… - … Pharmaceutica Sinica B, 2021 - Elsevier
The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …
[HTML][HTML] Biomaterial based modulation of macrophage polarization: a review and suggested design principles
Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …
however, their role in healing is being increasingly recognized in recent years due to their …
Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting
Hydrogels are a three-dimensional and crosslinked network of hydrophilic polymers. They
can absorb a large amount of water or biological fluids, which leads to their swelling while …
can absorb a large amount of water or biological fluids, which leads to their swelling while …