Risk factors for breast cancer in women: an update review

N Fakhri, MA Chad, M Lahkim, A Houari, H Dehbi… - Medical Oncology, 2022 - Springer
Breast Cancer remains, according to the World Health Organization, the most complex
disease cancer in 2021 in the world and the most common cause of death among women …

Global epidemiology of breast cancer based on risk factors: a systematic review

A Roheel, A Khan, F Anwar, Z Akbar, MF Akhtar… - Frontiers in …, 2023 - frontiersin.org
Background Numerous reviews of the epidemiology and risk factors for breast cancer have
been published previously which heighted different directions of breast cancer. Aim The …

The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology

KA Hirko, G Rocque, E Reasor, A Taye, A Daly… - BMC medicine, 2022 - Springer
Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading
causes of cancer death. The incidence, pathological features, and clinical outcomes in …

Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry …

M Miyashita, JSK Bell, S Wenric, E Karaesmen… - Breast Cancer …, 2023 - Springer
Abstract Background Endocrine-resistant HR+/HER2-breast cancer (BC) and triple-negative
BC (TNBC) are of interest for molecularly informed treatment due to their aggressive natures …

Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers

WM Alenezi, CT Fierheller, N Recio, PN Tonin - Genes, 2020 - mdpi.com
Soon after the discovery of BRCA1 and BRCA2 over 20 years ago, it became apparent that
not all hereditary breast and/or ovarian cancer syndrome families were explained by …

Disparities in genetic testing and care among black women with hereditary breast cancer

S Reid, S Cadiz, T Pal - Current breast cancer reports, 2020 - Springer
Abstract Purpose of Review Despite a steady improvement in breast cancer survival rates
over the past several decades, mortality disparities remain among Black women, who have …

Relative impact of genetic ancestry and neighborhood socioeconomic status on all-cause mortality in self-identified African Americans

HS Iyer, SL Gomez, I Cheng, TR Rebbeck - PLoS One, 2022 - journals.plos.org
Self-identified race/ethnicity is a correlate of both genetic ancestry and socioeconomic
factors, both of which may contribute to racial disparities in mortality. Investigators often hold …

Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience

NC Van der Merwe, HME Combrink, KS Ntaita… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is a multifaceted disease that currently represents a leading cause of death in
women worldwide. Over the past two decades (1998–2020), the National Health Laboratory …

Leveraging genetic ancestry to study health disparities

K Batai, S Hooker, RA Kittles - American Journal of Physical …, 2021 - Wiley Online Library
Research to understand human genomic variation and its implications in health has great
potential to contribute in the reduction of health disparities. Biological anthropology can play …

Gene sequencing for pathogenic variants among adults with breast and ovarian cancer in the caribbean

SHL George, T Donenberg, C Alexis… - JAMA network …, 2021 - jamanetwork.com
Importance Rates of breast and ovarian cancer are high in the Caribbean; however, to date,
few published data quantify the prevalence of inherited cancer in the Caribbean population …