[HTML][HTML] Role of gut microbial metabolites in cardiovascular diseases—current insights and the road ahead
Cardiovascular diseases (CVDs) are the leading cause of premature morbidity and mortality
globally. The identification of novel risk factors contributing to CVD onset and progression …
globally. The identification of novel risk factors contributing to CVD onset and progression …
Cardiovascular diseases and zinc
Zinc is structurally and functionally essential for more than 300 enzymes and 2000
transcription factors in human body. Intracellular labile zinc is the metabolically effective zinc …
transcription factors in human body. Intracellular labile zinc is the metabolically effective zinc …
Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha–Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in …
Background: Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular
death in low-and middle-income countries and affects predominantly women. The …
death in low-and middle-income countries and affects predominantly women. The …
Cellular mechanisms and molecular pathways linking bitter taste receptor signalling to cardiac inflammation, oxidative stress, arrhythmia and contractile dysfunction in …
MO Welcome, D Dogo, NE Mastorakis - Inflammopharmacology, 2023 - Springer
Heart diseases and related complications constitute a leading cause of death and
socioeconomic threat worldwide. Despite intense efforts and research on the pathogenetic …
socioeconomic threat worldwide. Despite intense efforts and research on the pathogenetic …
Transcatheter heart valve interventions for patients with rheumatic heart disease
Rheumatic heart disease [RHD] is the most prevalent cause of valvular heart disease in the
world, outstrip** degenerative aortic stenosis numbers fourfold. Despite this, global …
world, outstrip** degenerative aortic stenosis numbers fourfold. Despite this, global …
Cellular landscapes of nondiseased human cardiac valves from end-stage heart failure–explanted heart
S Shu, M Fu, X Chen, N Zhang, R Zhao… - … and Vascular Biology, 2022 - Am Heart Assoc
Background: Exploring the mechanisms of valvular heart disease at the cellular level may be
useful to identify new therapeutic targets; however, the comprehensive cellular landscape of …
useful to identify new therapeutic targets; however, the comprehensive cellular landscape of …
The role of inflammation and oxidative stress in rheumatic heart disease
B Franczyk, A Gluba-Brzózka… - International Journal of …, 2022 - mdpi.com
Rheumatic heart disease (RHD), an acquired valvular disease, remains an important cause
of morbidity and mortality in develo** countries. This chronic illness starts from untreated …
of morbidity and mortality in develo** countries. This chronic illness starts from untreated …
Multiscale structure and function of the aortic valve apparatus
Whereas studying the aortic valve in isolation has facilitated the development of life-saving
procedures and technologies, the dynamic interplay of the aortic valve and its surrounding …
procedures and technologies, the dynamic interplay of the aortic valve and its surrounding …
Profibrotic VEGFR3-dependent lymphatic vessel growth in autoimmune valvular carditis
V Osinski, A Yellamilli, MM Firulyova… - … , and vascular biology, 2024 - Am Heart Assoc
BACKGROUND: Rheumatic heart disease is the major cause of valvular heart disease in
develo** nations. Endothelial cells (ECs) are considered crucial contributors to rheumatic …
develo** nations. Endothelial cells (ECs) are considered crucial contributors to rheumatic …
Aortic stenosis and the haemostatic system
A Trimaille, S Hmadeh, K Matsushita… - Cardiovascular …, 2023 - academic.oup.com
Aortic stenosis (AS) affects more than 10% of the population over 80 years of age and
constitutes a major risk factor for heart failure, thromboembolic stroke, and death. A better …
constitutes a major risk factor for heart failure, thromboembolic stroke, and death. A better …