Survival in glioblastoma: a review on the impact of treatment modalities

PD Delgado-López, EM Corrales-García - Clinical and Translational …, 2016 - Springer
Glioblastoma (GBM) is the most common and lethal tumor of the central nervous system. The
natural history of treated GBM remains very poor with 5-year survival rates of 5%. Survival …

Tumor-treating fields: a fourth modality in cancer treatment

EJ Mun, HM Babiker, U Weinberg… - Clinical Cancer …, 2018 - aacrjournals.org
Despite major advances in therapy, cancer continues to be a leading cause of mortality. In
addition, toxicities of traditional therapies pose a significant challenge to tolerability and …

Mitotic spindle disruption by alternating electric fields leads to improper chromosome segregation and mitotic catastrophe in cancer cells

M Giladi, RS Schneiderman, T Voloshin, Y Porat… - Scientific reports, 2015 - nature.com
Abstract Tumor Treating Fields (TTFields) are low intensity, intermediate frequency,
alternating electric fields. TTFields are a unique anti-mitotic treatment modality delivered in a …

[PDF][PDF] The mechanisms of action of tumor treating fields

JC Moser, E Salvador, K Deniz, K Swanson… - Cancer …, 2022 - aacrjournals.org
Abstract Tumor Treating Fields (TTFields), a new modality of cancer treatment, are electric
fields transmitted transdermally to tumors. The FDA has approved TTFields for the treatment …

Virtual human models for electromagnetic studies and their applications

SN Makarov, GM Noetscher… - IEEE reviews in …, 2017 - ieeexplore.ieee.org
Numerical simulation of electromagnetic, thermal, and mechanical responses of the human
body to different stimuli in magnetic resonance imaging safety, antenna research …

Tumor treating fields in the management of patients with malignant gliomas

AP Ghiaseddin, D Shin, K Melnick, DD Tran - Current treatment options in …, 2020 - Springer
Opinion statement Malignant gliomas remain a challenging cancer to treat due to limitations
in both therapeutic and efficacious options. Tumor treating fields (TTFields) have emerged …

How to target inter-regional phase synchronization with dual-site transcranial alternating current stimulation

GB Saturnino, KH Madsen, HR Siebner, A Thielscher - Neuroimage, 2017 - Elsevier
Large-scale synchronization of neural oscillations is a key mechanism for functional
information exchange among brain areas. Dual-site Transcranial Alternating Current …

A review on tumor-treating fields (TTFields): clinical implications inferred from computational modeling

C Wenger, PC Miranda, R Salvador… - IEEE Reviews in …, 2018 - ieeexplore.ieee.org
Tumor-treating fields (TTFields) are a cancer treatment modality that uses alternating electric
fields of intermediate frequency (~ 100-500 kHz) and low intensity (1-3 V/cm) to disrupt cell …

Electrotherapies for glioblastoma

EPW Jenkins, A Finch, M Gerigk, IF Triantis… - Advanced …, 2021 - Wiley Online Library
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

[HTML][HTML] Progress and prospect in tumor treating fields treatment of glioblastoma

S Liu, W Shi, Q Zhao, Z Zheng, Z Liu, L Meng… - Biomedicine & …, 2021 - Elsevier
Glioblastoma (GBM) is a challenging cancer with poor prognosis. The classical standard for
treatment is safe resection, followed by concurrent chemoradiotherapy with subsequent …