Inherited platelet disorders resulting from platelet function defects and a normal platelet
count cause a moderate or severe bleeding diathesis. Since the description of Glanzmann …

The inherited platelet glycoprotein deficiencies, Glanzmann thrombasthenia (GT) and
Bernard Soulier syndrome (BSS) are rare but important long‐term bleeding disorders. Once …

Excessive bleeding at surgery is a feared complication in patients with inherited platelet
disorders. However, very few studies have evaluated the frequency of surgical bleeding in …

Platelet dense-granules are small organelles specific to the platelet lineage that contain
small molecules (calcium, adenyl nucleotides, serotonin) and are essential for the activation …

Background Platelet count alone does not reliably predict bleeding risk, suggesting platelet
function is important to monitor in patients with thrombocytopenia. There is still an unmet …

Abstract Background The ISTH Bleeding Assessment Tool (ISTH‐BAT) has been validated
for clinical screening of suspected von Willebrand disease (VWD) and for bleeding …

Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by a
quantitative and/or qualitative defect of the αIIbβ3 integrin. Pregnancy and delivery are …

Abstract Background Inherited platelet disorders (IPDs) are rare diseases characterized by
reduced blood platelet counts and/or impaired platelet function. Recognizing IPDs is …

Invasive placentation with extended pregnancy is a shared derived characteristic unique to
eutherian mammals that possess a highly effective system of haemostasis, platelets. These …

Background Although flow cytometry is often brought forward as a preferable method in the
setting of thrombocytopenia, the relative effects of low sample counts on results from flow …