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Structural components of synaptic plasticity and memory consolidation
CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …
mammalian hippocampus are associated with remodeling and growth of preexisting …
Autoimmune seizures and epilepsy
C Geis, J Planagumà, M Carreño, F Graus… - The Journal of clinical …, 2019 - jci.org
The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …
Synaptic nanomodules underlie the organization and plasticity of spine synapses
M Hruska, N Henderson, SJ Le Marchand, H Jafri… - Nature …, 2018 - nature.com
Experience results in long-lasting changes in dendritic spine size, yet how the molecular
architecture of the synapse responds to plasticity remains poorly understood. Here a …
architecture of the synapse responds to plasticity remains poorly understood. Here a …
Synaptic plasticity, dementia and Alzheimer disease
SD Skaper, L Facci, M Zusso… - CNS & Neurological …, 2017 - ingentaconnect.com
Neuroplasticity is not only shaped by learning and memory but is also a mediator of
responses to neuron attrition and injury (compensatory plasticity). As an ongoing process it …
responses to neuron attrition and injury (compensatory plasticity). As an ongoing process it …
Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis
L Mikasova, P De Rossi, D Bouchet, F Georges… - Brain, 2012 - academic.oup.com
Autoimmune synaptic encephalitides are recently described human brain diseases leading
to psychiatric and neurological syndromes through inappropriate brain–autoantibody …
to psychiatric and neurological syndromes through inappropriate brain–autoantibody …
Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
HO Kalkman, D Feuerbach - Cellular and molecular life sciences, 2016 - Springer
The clinical development of selective alpha-7 nicotinic acetylcholine receptor (α7 nAChR)
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …
Ephrin‐B2 prevents N‐methyl‐D‐aspartate receptor antibody effects on memory and neuroplasticity
J Planagumà, H Haselmann, F Mannara… - Annals of …, 2016 - Wiley Online Library
Objective To demonstrate that ephrin‐B2 (the ligand of EphB2 receptor) antagonizes the
pathogenic effects of patients' N‐methyl‐D‐aspartate receptor (NMDAR) antibodies on …
pathogenic effects of patients' N‐methyl‐D‐aspartate receptor (NMDAR) antibodies on …
Metabotropic NMDA receptor function is required for β-amyloid–induced synaptic depression
The mechanisms by which β-amyloid (Aβ), a peptide fragment believed to contribute to
Alzheimer's disease, leads to synaptic deficits are not known. Here we find that elevated …
Alzheimer's disease, leads to synaptic deficits are not known. Here we find that elevated …
Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific
Heterotetrameric glutamate receptors are essential for the development, function, and
plasticity of spine synapses but how they are organized to achieve this is not known. Here …
plasticity of spine synapses but how they are organized to achieve this is not known. Here …
NMDA receptor activity in neuropsychiatric disorders
SE Lakhan, M Caro, N Hadzimichalis - Frontiers in psychiatry, 2013 - frontiersin.org
N-Methyl-d-aspartate (NMDA) receptors play a variety of physiologic roles and their proper
signaling is essential for cellular homeostasis. Any disruption in this pathway, leading to …
signaling is essential for cellular homeostasis. Any disruption in this pathway, leading to …