Immunotherapy in renal cell carcinoma: the future is now

A Deleuze, J Saout, F Dugay, B Peyronnet… - International Journal of …, 2020 - mdpi.com
Renal cell carcinoma is the third type of urologic cancer and has a poor prognosis with 30%
of metastatic patients at diagnosis. The antiangiogenics and targeted immunotherapies led …

Sarcomatoid renal cell carcinoma: biology, natural history and management

KA Blum, S Gupta, SK Tickoo, TA Chan… - Nature Reviews …, 2020 - nature.com
Sarcomatoid dedifferentiation is an uncommon feature that can occur in most histological
subtypes of renal cell carcinomas (RCCs) and carries a decidedly poor prognosis …

[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia

K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …

Hereditary leiomyomatosis and renal cell cancer (HLRCC): renal cancer risk, surveillance and treatment

FH Menko, ER Maher, LS Schmidt, LA Middelton… - Familial cancer, 2014 - Springer
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant
condition in which susceptible individuals are at risk for the development of cutaneous …

WHO/ISUP classification, grading and pathological staging of renal cell carcinoma: standards and controversies

AY Warren, D Harrison - World journal of urology, 2018 - Springer
Purpose Pathological parameters assessed on biopsies and resection specimens have a
pivotal role in the diagnosis, prognosis and management of patients with renal cell …

Hereditary renal cell carcinoma syndromes: diagnosis, surveillance and management

ER Maher - World journal of urology, 2018 - Springer
Purpose Genetic factors have been implicated in the pathogenesis of renal cell carcinoma
(RCC), with around 3% of cases having a family history. A greater knowledge of the genetics …

Fumarate hydratase–deficient renal cell carcinoma is strongly correlated with fumarate hydratase mutation and hereditary leiomyomatosis and renal cell carcinoma …

K Trpkov, O Hes, A Agaimy, M Bonert… - The American journal …, 2016 - journals.lww.com
Hereditary leiomyomatosis and renal cell carcinoma syndrome–associated renal cell
carcinomas (RCC) are difficult to diagnose prospectively. We used immunohistochemistry …

Papillary renal cell carcinoma (PRCC): an update

M Akhtar, IA Al-Bozom, T Al Hussain - Advances in anatomic …, 2019 - journals.lww.com
Papillary renal cell carcinoma (PRCC) is the second most common type of renal carcinoma
following clear cell renal cell carcinoma. Papillary renal cell carcinoma is usually divided …

New and emerging renal entities: a perspective post‐WHO 2016 classification

K Trpkov, O Hes - Histopathology, 2019 - Wiley Online Library
Renal tumours include a heterogeneous and diverse spectrum of neoplasms. Recent
advances in this field have significantly improved our understanding of the morphological …

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

YB Chen, J Xu, AJ Skanderup, Y Dong… - Nature …, 2016 - nature.com
Renal cell carcinomas with unclassified histology (uRCC) constitute a significant portion of
aggressive non-clear cell renal cell carcinomas that have no standard therapy. The …