Thrombophilia, risk factors and prevention

E Campello, L Spiezia, A Adamo… - Expert review of …, 2019 - Taylor & Francis
Introduction: Fifty-three years after the first description of an inherited prothrombotic
condition (antithrombin deficiency), our knowledge on hereditary and acquired causes of …

Genetic risk factors for venous thromboembolism

B Zöller, PJ Svensson, B Dahlbäck… - Expert Review of …, 2020 - Taylor & Francis
Introduction Venous thromboembolism (VTE) is a complex disease that aggregates in
families. Both acquired and genetic risk factors are important. Proper recognition and …

Thrombin generation in patients with COVID-19 with and without thromboprophylaxis

E Campello, C Bulato, L Spiezia, A Boscolo… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Thrombin generation (TG) with and without thrombomodulin (TM) was evaluated
in COVID-19 patients with different disease severity and thromboprophylaxis regimen, in …

The Role of Biomarkers, Metabolomics, and COVID-19 in Venous Thromboembolism—A Review of Literature

V Della Corte, R Riolo, S Scaglione… - International Journal of …, 2023 - mdpi.com
In recent years, the field of venous thromboembolism has undergone numerous innovations,
starting from the recent discoveries on the role of biomarkers, passing through the role of …

Direct oral anticoagulants in patients with inherited thrombophilia and venous thromboembolism: a prospective cohort study

E Campello, L Spiezia, C Simion… - Journal of the …, 2020 - Am Heart Assoc
Background In this prospective cohort study, we aimed to evaluate the efficacy and safety of
direct oral anticoagulants (DOACs) versus heparin/vitamin K antagonists for the treatment of …

Snake venoms in diagnostic hemostasis and thrombosis

GW Moore - Seminars in thrombosis and hemostasis, 2022 - thieme-connect.com
Snake venoms have evolved primarily to immobilize and kill prey, and consequently, they
contain some of the most potent natural toxins. Part of that armory is a range of hemotoxic …

Partial F8 gene duplication (factor VIII Padua) associated with high factor VIII levels and familial thrombophilia

P Simioni, S Cagnin, F Sartorello… - Blood, The Journal …, 2021 - ashpublications.org
High coagulation factor VIII (FVIII) levels comprise a common risk factor for venous
thromboembolism (VTE), but the underlying genetic determinants are largely unknown. We …

Diagnosis and management of factor V Leiden

E Campello, L Spiezia, P Simioni - Expert review of hematology, 2016 - Taylor & Francis
Introduction: The discovery of the factor V Leiden (FVL) missense mutation (Arg506Gln)
causing factor V resistance to the anticoagulant action of activated protein C was a landmark …

What is currently known about the genetics of venous thromboembolism at the dawn of next generation sequencing technologies

DA Trégouët, PE Morange - British journal of haematology, 2018 - Wiley Online Library
Venous thromboembolism (VTE) has a strong genetic component. This review summarizes
what is known at the seventeen genes that are now well established to harbour VTE …

Reversal of hypercoagulability in patients with HCV‐related cirrhosis after treatment with direct‐acting antivirals

FP Russo, A Zanetto, E Campello, C Bulato… - Liver …, 2018 - Wiley Online Library
Abstract Background & Aims The long‐term impact of sustained virological response (SVR)
after direct‐acting antivirals (DAA s) on the hypercoagulability associated with HCV cirrhosis …