An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

K Saliminejad, HR Khorram Khorshid… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in
posttranscriptional regulation of gene expression. They are powerful regulators of various …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Identification of lncRNA/circRNA-miRNA-mRNA ceRNA network as biomarkers for hepatocellular carcinoma

S Chen, Y Zhang, X Ding, W Li - Frontiers in genetics, 2022 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) accounts for the majority of liver cancer, with
the incidence and mortality rates increasing every year. Despite the improvement of clinical …

Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application

YM Sun, YQ Chen - Journal of hematology & oncology, 2020 - Springer
Noncoding RNAs (ncRNAs) are a large segment of the transcriptome that do not have
apparent protein-coding roles, but they have been verified to play important roles in diverse …

CancerMIRNome: an interactive analysis and visualization database for miRNome profiles of human cancer

R Li, H Qu, S Wang, JM Chater, X Wang… - Nucleic acids …, 2022 - academic.oup.com
MicroRNAs (miRNAs), which play critical roles in gene regulatory networks, have emerged
as promising diagnostic and prognostic biomarkers for human cancer. In particular …

Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective

M Kori, K Yalcin Arga - PLoS One, 2018 - journals.plos.org
The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway

X Li, N Ma, Y Zhang, H Wei, H Zhang, X Pang, X Li… - Cell death & …, 2020 - nature.com
Emerging evidence indicates that circRNAs play essential roles in tumorigenesis and
development. However, the role of circRNAs in cervical cancer (CC) remains unclear …

CMC: Cancer miRNA Census–a list of cancer-related miRNA genes

M Suszynska, M Machowska, E Fraszczyk… - Nucleic Acids …, 2024 - academic.oup.com
A growing body of evidence indicates an important role of miRNAs in cancer; however, there
is no definitive, convenient-to-use list of cancer-related miRNAs or miRNA genes that may …