[HTML][HTML] Unraveling the Potential of γ-Aminobutyric Acid: Insights into Its Biosynthesis and Biotechnological Applications

L Zhu, Z Wang, L Gao, X Chen - Nutrients, 2024 - mdpi.com
γ-Aminobutyric acid (GABA) is a widely distributed non-protein amino acid that serves as a
crucial inhibitory neurotransmitter in the brain, regulating various physiological functions. As …

Efficient production of γ-aminobutyric acid using engineered Escherichia coli whole-cell catalyst

F Chang, Y Wang, J Zhang, T Tu, H Luo… - Enzyme and Microbial …, 2024 - Elsevier
Abstract γ-Aminobutyric acid (GABA) has been widely used in the food, feed,
pharmaceutical, and chemical industry fields. Previously, we developed a whole-cell catalyst …

Sustainable production of 4-aminobutyric acid (GABA) and cultivation of Chlorella sorokiniana and Chlorella vulgaris as circular economy

C Xue, IS Ng - Bioresource technology, 2022 - Elsevier
Abstract The 4-aminobutyric acid (GABA) is important to produce bio-nylon 4 in biorefineries.
First, a glutamate decarboxylase (GAD) was propagated in three different Escherichia coli …

Engineered Halomonas for production of gamma-aminobutyric acid and 2-pyrrolidone

G Zhang, W Guo, X Yi, Z Zhang, L Zhang, X Liu… - Bioresource …, 2024 - Elsevier
Gamma-Aminobutyric acid (GABA) is a derivative of L-glutamate, also a precursor for the
synthesis of 2-pyrrolidone, which is a monomer of nylon-4. This study achieved a one-step …

Discovery and characterization of temperature adaptation modules by mining L-glutamate decarboxylase derived from psychrophilic microorganisms

C Song, J Luo, J Qiao, Z Liu, Z Cheng, Q Wang… - International Journal of …, 2024 - Elsevier
Directed alterations of the enzyme's temperature adaptations, such as thermostability and
optimal catalytic temperature (T opt), are usually the way to go in order to meet the …

[HTML][HTML] Whole-Cell Display of Phosphotransferase in Escherichia coli for High-Efficiency Extracellular ATP Production

S Zhao, G Yang, X **e, G Yan, F Wang, W Chen, L Ma - Biomolecules, 2022 - mdpi.com
Adenosine triphosphate (ATP), as a universal energy currency, takes a central role in many
biochemical reactions with potential for the synthesis of numerous high-value products …

Efficient Whole-cell Catalysis for γ-Aminobutyric Acid Production Using Engineered Escherichia coli

F Chang, Y Wang, J Zhang, T Tu, H Luo, H Huang… - 2023 - researchsquare.com
Background γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid that has
extensive applications in the food, feed, pharmaceutical, and chemical synthesis fields. The …