Progresses and prospects of neuroprotective agents-loaded nanoparticles and biomimetic material in ischemic stroke
J Chen, J **, K Li, L Shi, X Wen, F Fang - Frontiers in Cellular …, 2022 - frontiersin.org
Ischemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …
Recent advances in chemically engineered nanostructures impact on ischemic stroke treatment
G Sri Kanaka Durga Vijayalakshmi, N Puvvada - ACS omega, 2023 - ACS Publications
Stroke is a serious public health problem that raises expenses for society and causes long-
term impairment and death. However, due to restricted blood–brain barrier (BBB) …
term impairment and death. However, due to restricted blood–brain barrier (BBB) …
Protein kinase C-delta inhibition protects blood-brain barrier from sepsis-induced vascular damage
Background Neuroinflammation often develops in sepsis leading to activation of cerebral
endothelium, increased permeability of the blood-brain barrier (BBB), and neutrophil …
endothelium, increased permeability of the blood-brain barrier (BBB), and neutrophil …
[HTML][HTML] Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial …
S Chen, M Sun, X Zhao, Z Yang… - Molecular …, 2019 - spandidos-publications.com
Stroke is the second most frequent cause of mortality, resulting in a huge societal burden
worldwide. Timely reperfusion is the most effective therapy; however, it is difficult to prevent …
worldwide. Timely reperfusion is the most effective therapy; however, it is difficult to prevent …
Nanocarriers for stroke therapy: advances and obstacles in translating animal studies
SA Alkaff, K Radhakrishnan… - International journal …, 2020 - Taylor & Francis
The technology of drug delivery systems (DDS) has expanded into many applications, such
as for treating neurological disorders. Nanoparticle DDS offer a unique strategy for targeted …
as for treating neurological disorders. Nanoparticle DDS offer a unique strategy for targeted …
Burns impair blood-brain barrier and mesenchymal stem cells can reverse the process in mice
J Yang, K Ma, C Zhang, Y Liu, F Liang, W Hu… - Frontiers in …, 2020 - frontiersin.org
Neurological syndromes are observed in numerous patients who suffer burns, which add to
the economic burden of societies and families. Recent studies have implied that blood–brain …
the economic burden of societies and families. Recent studies have implied that blood–brain …
Post-ischemic administration of dopamine D2 receptor agonist reduces cell death by activating mitochondrial pathway following ischemic stroke
Aims Cerebral ischemic stroke leads to mitochondrial alterations which are key factors for
initiation of various cascades resulting in neuronal damage. Dopamine D2 receptor (D2R) …
initiation of various cascades resulting in neuronal damage. Dopamine D2 receptor (D2R) …
The effect of sevoflurane and fullerenol C 60 on the liver and kidney in lower extremity ischemia-reperfusion injury in mice with streptozocin-induced diabetes
N Şengel, A Küçük, Ç Özdemir, ŞC Sezen… - International Journal …, 2023 - Taylor & Francis
Objective This study aimed to demonstrate whether fullerenol C60, sevoflurane anesthesia,
or a combination of both had protective effects on the liver and kidneys in lower extremity …
or a combination of both had protective effects on the liver and kidneys in lower extremity …
Insight on bacterial newborn meningitis using a neurovascular-unit-on-a-chip
R Rauti, S Navok, D Biran, K Tadmor… - Microbiology …, 2023 - Am Soc Microbiol
Understanding the pathogenesis of bacterial infections is critical for combatting them. For
some infections, animal models are inadequate and functional genomic studies are not …
some infections, animal models are inadequate and functional genomic studies are not …
Wielding the double‐edged sword of inflammation: building biomaterial‐based strategies for immunomodulation in ischemic stroke treatment
N Letko Khait, E Ho, MS Shoichet - Advanced Functional …, 2021 - Wiley Online Library
Stroke is a leading cause of disability with no current treatment to regenerate lost brain
tissue. Innovative preclinical and clinical trials have attempted to improve stroke recovery by …
tissue. Innovative preclinical and clinical trials have attempted to improve stroke recovery by …