Advances in adoptive T-cell therapy for metastatic melanoma

A Das, A Ghose, K Naicker, E Sanchez… - Current research in …, 2023 - Elsevier
Adoptive T cell therapy (ACT) is a fast develo**, niche area of immunotherapy (IO), which
is revolutionising the therapeutic landscape of solid tumour oncology, especially metastatic …

Insights into Cancer Immunotherapies: Recent Breakthroughs, Opportunities, and Challenges

EG Pappas, MH Kershaw, CY Slaney - Cancers, 2023 - mdpi.com
This Special Issue reminds us that, although incredible developments have occurred in the
field of cancer immunotherapy, there is still plenty of room for improvement. Although many …

Synthetic Lethality Screening with Recursive Feature Machines

C Cai, A Radhakrishnan, C Uhler - bioRxiv, 2023 - pmc.ncbi.nlm.nih.gov
Synthetic lethality refers to a genetic interaction where the simultaneous perturbation of
gene pairs leads to cell death. Synthetically lethal gene pairs (SL pairs) provide a potential …

Machine Learning Methods for Learning Genetic Dependencies

C Cai - 2024 - dspace.mit.edu
Synthetic lethality refers to a genetic interaction where the simultaneous perturbation of
gene pairs leads to cell death. Synthetically lethal gene pairs (SL pairs) provide a potential …