A bdominal aortic aneurysm (AAA) is a common problem with life-threatening
consequences. Although the threat of ruptured AAAs has captured the attention of surgeons …

Hintergrund: Die Kalzifizierung der arteriellen Gefäßwand kann mit unterschiedlicher
Lokalisation in der Intima oder aber der Media stattfinden. Die Kalzifizierung der Intima …

Using DNA microarray screening (GeneFilter 211, Research Genetics, Huntsville, AL) of
mRNA from primary human umbilical vein endothelial cells (HUVEC), we identified 52 …

Elastin-derived peptides display a wide range of biological activities in a number of normal
and transformed cells but their involvement in angiogenesis has not been reported. In the …

The fact that elastin peptides, the degradation products of the extracellular matrix protein
elastin, are chemotactic for numerous cell types, promote cell cycle progression and induce …

Degradation of elastin, the main amorphous component of elastic fibers, by elastases
belonging to the serine, metallo, or cysteine families leads to the generation of elastin …

Skin is an important organ to the human body as it functions as an interface between the
body and environment. Cutaneous injury elicits a complex wound healing process, which is …

Once considered as inert, the extracellular matrix recently revealed to be biologically active.
Elastin is one of the most important components of the extracellular matrix. Many vital organs …

Evolution of species has led to the appearance of circulatory systems including blood
vessels and one or more pulsatile pumps, typically resulting in a low-pressurised open …

Elastin is synthesized and secreted by vascular smooth muscle cells and is the major
extracellular matrix component deposited in the arterial wall. When last reviewed by this …