Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response
BP Todd, MS Chimenti, Z Luo, PJ Ferguson… - Journal of …, 2021 - Springer
Background Traumatic brain injury (TBI) is a leading cause of death and disability that lacks
neuroprotective therapies. Following a TBI, secondary injury response pathways are …
neuroprotective therapies. Following a TBI, secondary injury response pathways are …
Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury
Background Traumatic brain injury (TBI) is characterized by massive changes in neuronal
excitation, from acute excitotoxicity to chronic hyper-or hypoexcitability. Nuclear calcium …
excitation, from acute excitotoxicity to chronic hyper-or hypoexcitability. Nuclear calcium …
Post-traumatic Epilepsy and Neuropsychiatric Comorbidities
Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that arises from traumatic brain
injury (TBI). It presents a complex relationship with various neuropsychiatric comorbidities …
injury (TBI). It presents a complex relationship with various neuropsychiatric comorbidities …
[PDF][PDF] Transcriptional Plasticity of Microglia During Intraocular Inflammation
O Bell - 2021 - research-information.bris.ac.uk
Microglia are a tissue-resident immune cell of the central nervous system known to possess
functions involved in immune surveillance and tissue homeostasis. Transcriptomics has …
functions involved in immune surveillance and tissue homeostasis. Transcriptomics has …