Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

[HTML][HTML] Targeted drug delivery systems for elemene in cancer therapy: The story thus far

H Tian, F Zhao, Q Qi, B Yue, B Zhai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Elemene (ELE) is a group of broad-spectrum anticancer active ingredients with low toxicity
extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and …

Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity

Y Li, W Chen, Y Kang, X Zhen, Z Zhou, C Liu… - Nature …, 2023 - nature.com
The dense stroma of desmoplastic tumor limits nanotherapeutic penetration and hampers
the antitumor immune response. Here, we report a denaturation-and-penetration strategy …

Biointerface‐Engineered Hybrid Nanovesicles for Targeted Reprogramming of Tumor Microenvironment

X Zhen, Y Li, W Yuan, T Zhang, M Li… - Advanced …, 2024 - Wiley Online Library
The tumor microenvironment (TME) of typical tumor types such as triple‐negative breast
cancer is featured by hypoxia and immunosuppression with abundant tumor‐associated …

Endogenous zinc‐ion‐triggered in situ gelation enables Zn capture to reprogram benign hyperplastic prostate microenvironment and shrink prostate

J Ge, C Fang, H Tan, M Zhan, M Gu, J Ni… - Advanced …, 2024 - Wiley Online Library
Benign prostatic hyperplasia (BPH) as the leading cause of urination disorder is still a
refractory disease, and there have no satisfied drugs or treatment protocols yet. With …

High Entropy 2D Layered Double Hydroxide Nanosheet Toward Cascaded Nanozyme-Initiated Chemodynamic and Immune Synergistic Therapy

C Wang, F Yuan, Z Yan, T Zhang, C Fu… - Journal of the …, 2024 - ACS Publications
High-entropy nanomaterials (HEMs) are a hot topic in the fields of energy and catalysis.
However, in terms of promising biomedical applications, potential therapeutic studies …

[HTML][HTML] β-Elemene induced ferroptosis via TFEB-mediated GPX4 degradation in EGFR wide-type non-small cell lung cancer

LP Zhao, HJ Wang, D Hu, JH Hu, ZR Guan… - Journal of Advanced …, 2024 - Elsevier
Introduction β-Elemene (β-ELE), derived from Curcuma wenyu**, has anticancer effect on
non-small cell lung cancer (NSCLC). However, the potential target and detail mechanism …

Autophagy‐Inducing MoO3‐x Nanowires Boost Photothermal‐Triggered Cancer Immunotherapy

L He, Q Chen, Q Lu, M Yang, B **e, T Chen… - Angewandte …, 2024 - Wiley Online Library
Autophagy could play suppressing role in cancer therapy by facilitating release of tumor
antigens from dying cells and inducing immunogenic cell death (ICD). Therefore, discovery …

Unimolecular self-assembled hemicyanine–oleic acid conjugate acts as a novel succinate dehydrogenase inhibitor to amplify photodynamic therapy and eliminate …

Q Wang, T Yang, S Li, C Xu, C Wang, Y **ong, X Wang… - Research, 2023 - spj.science.org
Photodynamic therapy with reactive oxygen species production is a prospective treatment to
combat cancer stem cells (CSCs). However, the innate drawbacks, including short lifetime …

Macrophage-modulating nanomedicine for cancer immunotherapy

MM Khan, Y Li, Z Zhou, A Ni, Q Saiding, D Qin, W Tao… - Nanoscale, 2024 - pubs.rsc.org
Tumor-associated macrophages (TAMs) play crucial roles in the immunosuppressive solid
tumor microenvironment (TME). Despite their tumor-promoting functions, TAMs can also be …