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Ultrasound-based micro-/nanosystems for biomedical applications
H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …
[HTML][HTML] Targeted drug delivery systems for elemene in cancer therapy: The story thus far
H Tian, F Zhao, Q Qi, B Yue, B Zhai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Elemene (ELE) is a group of broad-spectrum anticancer active ingredients with low toxicity
extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and …
extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and …
Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity
The dense stroma of desmoplastic tumor limits nanotherapeutic penetration and hampers
the antitumor immune response. Here, we report a denaturation-and-penetration strategy …
the antitumor immune response. Here, we report a denaturation-and-penetration strategy …
Biointerface‐Engineered Hybrid Nanovesicles for Targeted Reprogramming of Tumor Microenvironment
The tumor microenvironment (TME) of typical tumor types such as triple‐negative breast
cancer is featured by hypoxia and immunosuppression with abundant tumor‐associated …
cancer is featured by hypoxia and immunosuppression with abundant tumor‐associated …
Endogenous zinc‐ion‐triggered in situ gelation enables Zn capture to reprogram benign hyperplastic prostate microenvironment and shrink prostate
J Ge, C Fang, H Tan, M Zhan, M Gu, J Ni… - Advanced …, 2024 - Wiley Online Library
Benign prostatic hyperplasia (BPH) as the leading cause of urination disorder is still a
refractory disease, and there have no satisfied drugs or treatment protocols yet. With …
refractory disease, and there have no satisfied drugs or treatment protocols yet. With …
High Entropy 2D Layered Double Hydroxide Nanosheet Toward Cascaded Nanozyme-Initiated Chemodynamic and Immune Synergistic Therapy
C Wang, F Yuan, Z Yan, T Zhang, C Fu… - Journal of the …, 2024 - ACS Publications
High-entropy nanomaterials (HEMs) are a hot topic in the fields of energy and catalysis.
However, in terms of promising biomedical applications, potential therapeutic studies …
However, in terms of promising biomedical applications, potential therapeutic studies …
[HTML][HTML] β-Elemene induced ferroptosis via TFEB-mediated GPX4 degradation in EGFR wide-type non-small cell lung cancer
LP Zhao, HJ Wang, D Hu, JH Hu, ZR Guan… - Journal of Advanced …, 2024 - Elsevier
Introduction β-Elemene (β-ELE), derived from Curcuma wenyu**, has anticancer effect on
non-small cell lung cancer (NSCLC). However, the potential target and detail mechanism …
non-small cell lung cancer (NSCLC). However, the potential target and detail mechanism …
Autophagy‐Inducing MoO3‐x Nanowires Boost Photothermal‐Triggered Cancer Immunotherapy
L He, Q Chen, Q Lu, M Yang, B **e, T Chen… - Angewandte …, 2024 - Wiley Online Library
Autophagy could play suppressing role in cancer therapy by facilitating release of tumor
antigens from dying cells and inducing immunogenic cell death (ICD). Therefore, discovery …
antigens from dying cells and inducing immunogenic cell death (ICD). Therefore, discovery …
Unimolecular self-assembled hemicyanine–oleic acid conjugate acts as a novel succinate dehydrogenase inhibitor to amplify photodynamic therapy and eliminate …
Photodynamic therapy with reactive oxygen species production is a prospective treatment to
combat cancer stem cells (CSCs). However, the innate drawbacks, including short lifetime …
combat cancer stem cells (CSCs). However, the innate drawbacks, including short lifetime …
Macrophage-modulating nanomedicine for cancer immunotherapy
Tumor-associated macrophages (TAMs) play crucial roles in the immunosuppressive solid
tumor microenvironment (TME). Despite their tumor-promoting functions, TAMs can also be …
tumor microenvironment (TME). Despite their tumor-promoting functions, TAMs can also be …