The 5-point Investigator's Global Assessment (IGA) Scale: a modified tool for evaluating plaque psoriasis severity in clinical trials
RGB Langley, SR Feldman, J Nyirady… - Journal of …, 2015 - Taylor & Francis
Background: To evaluate new psoriasis treatments, clinicians, regulators and
pharmaceutical developers require well-accepted, clinically meaningful measures of …
pharmaceutical developers require well-accepted, clinically meaningful measures of …
What are the best outcome measures for assessing plaque psoriasis severity? A systematic review of the literature
E Puzenat, V Bronsard, S Prey… - Journal of the …, 2010 - Wiley Online Library
Background A wide variety of scoring systems have been proposed to assess severity of
psoriasis. Given its importance as a health issue both for patients and health care systems, it …
psoriasis. Given its importance as a health issue both for patients and health care systems, it …
Effect of therapeutic drug monitoring vs standard therapy during maintenance infliximab therapy on disease control in patients with immune-mediated inflammatory …
Importance Proactive therapeutic drug monitoring (TDM), consisting of individualized
treatment based on scheduled assessments of serum drug levels, has been proposed as an …
treatment based on scheduled assessments of serum drug levels, has been proposed as an …
Joint AAD–NPF Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity …
CA Elmets, NJ Korman, EF Prater, EB Wong… - Journal of the American …, 2021 - Elsevier
Psoriasis is a chronic, inflammatory, multisystem disease that affects up to 3.2% of the
United States population. This guideline addresses important clinical questions that arise in …
United States population. This guideline addresses important clinical questions that arise in …
Effect of therapeutic drug monitoring vs standard therapy during infliximab induction on disease remission in patients with chronic immune-mediated inflammatory …
Importance Proactive therapeutic drug monitoring (TDM), defined as individualized drug
dosing based on scheduled monitoring of serum drug levels, has been proposed as an …
dosing based on scheduled monitoring of serum drug levels, has been proposed as an …
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
W Hueber, DD Patel, T Dryja, AM Wright… - Science translational …, 2010 - science.org
Interleukin-17A (IL-17A) is elaborated by the T helper 17 (TH17) subset of TH cells and
exhibits potent proinflammatory properties in animal models of autoimmunity, including …
exhibits potent proinflammatory properties in animal models of autoimmunity, including …
Severity of psoriasis differs between men and women: a study of the clinical outcome measure psoriasis area and severity index (PASI) in 5438 Swedish register …
Background Psoriasis is a common skin disease and moderate to severe psoriasis is
associated with a dose-dependent risk for metabolic and cardiovascular morbidity. It has …
associated with a dose-dependent risk for metabolic and cardiovascular morbidity. It has …
[HTML][HTML] The reliability of three psoriasis assessment tools: Psoriasis area and severity index, body surface area and physician global assessment
A Bożek, A Reich - Advances in Clinical and Experimental …, 2017 - advances.umw.edu.pl
Background. A wide variety of psoriasis assessment tools have been proposed to evaluate
the severity of psoriasis in clinical trials and daily practice. The most frequently used clinical …
the severity of psoriasis in clinical trials and daily practice. The most frequently used clinical …
[HTML][HTML] How good are clinical severity and outcome measures for psoriasis?: quantitative evaluation in a systematic review
PI Spuls, LLA Lecluse, MLNF Poulsen, JD Bos… - Journal of Investigative …, 2010 - Elsevier
A large number of clinical measures of psoriasis are used in clinical trials and daily practice.
These measures lack uniformity and validation. However, valid outcome and severity …
These measures lack uniformity and validation. However, valid outcome and severity …
Physician Global Assessment (PGA) and Psoriasis Area and Severity Index (PASI): why do both? A systematic analysis of randomized controlled trials of biologic …
A Robinson, M Kardos, AB Kimball - Journal of the American Academy of …, 2012 - Elsevier
BACKGROUND: Although there are many psoriasis assessment tools currently published,
one of the unmet needs in psoriasis research remains consensus about the single best …
one of the unmet needs in psoriasis research remains consensus about the single best …