Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex
RZ Goldstein, ND Volkow - American journal of Psychiatry, 2002 - Am Psychiatric Assoc
OBJECTIVE: Studies of the neurobiological processes underlying drug addiction primarily
have focused on limbic subcortical structures. Here the authors evaluated the role of frontal …
have focused on limbic subcortical structures. Here the authors evaluated the role of frontal …
Insights into the neural basis of response inhibition from cognitive and clinical neuroscience
Neural mechanisms of cognitive control enable us to initiate, coordinate and update
behaviour. Central to successful control is the ability to suppress actions that are no longer …
behaviour. Central to successful control is the ability to suppress actions that are no longer …
Preschool program improves cognitive control
A Diamond, WS Barnett, J Thomas, S Munro - Science, 2007 - science.org
Results We report accuracy rather than speed because, for young children, accuracy is the
more sensitive measure (23). We conducted multiple regression analyses with age, gender …
more sensitive measure (23). We conducted multiple regression analyses with age, gender …
[BOK][B] Affect dysregulation and disorders of the self (Norton Series on Interpersonal Neurobiology)
A Schore - 2003 - books.google.com
This volume (one of two) is the first presentation of Schore's comprehensive theory in book
form, as it has developed since 1994. In 1994 Allan Schore published his groundbreaking …
form, as it has developed since 1994. In 1994 Allan Schore published his groundbreaking …
Neurobiologic processes in drug reward and addiction
B Adinoff - Harvard review of psychiatry, 2004 - Taylor & Francis
Neurophysiologic processes underlie the uncontrolled, compulsive behaviors defining the
addicted state. These “hard-wired” changes in the brain are considered critical for the …
addicted state. These “hard-wired” changes in the brain are considered critical for the …
Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task
Cocaine abusers demonstrate faulty decision-making as manifested by their inability to
discontinue self-destructive drug-seeking behaviors. The orbitofrontal cortex (OFC) plays an …
discontinue self-destructive drug-seeking behaviors. The orbitofrontal cortex (OFC) plays an …
Addiction, compulsive drug seeking, and the role of frontostriatal mechanisms in regulating inhibitory control
A principal feature of drug addiction is a reduced ability to regulate control over the desire to
procure drugs regardless of the risks involved. Traditional models implicated the neural …
procure drugs regardless of the risks involved. Traditional models implicated the neural …
Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies
ND Volkow, JS Fowler, GJ Wang… - Neurobiology of learning …, 2002 - Elsevier
Drug addiction is characterized by a set of recurring processes (intoxication, withdrawal,
craving) that lead to the relapsing nature of the disorder. We have used positron emission …
craving) that lead to the relapsing nature of the disorder. We have used positron emission …
Impaired decision making related to working memory deficits in individuals with substance addictions.
This study examined whether individuals with substance dependence (ISDs) show
impairments in working memory and whether there is a relationship between their …
impairments in working memory and whether there is a relationship between their …
Executive dysfunction in cocaine addiction: evidence for discordant frontal, cingulate, and cerebellar activity
Using a GO-NOGO response inhibition task in which working memory (WM) demands can
be varied, we demonstrate that the compromised abilities of cocaine users to exert control …
be varied, we demonstrate that the compromised abilities of cocaine users to exert control …