It is increasingly proposed that reactive oxygen species (ROS) and reactive nitrogen species
(RNS) play a key role in human cancer development [1–6], especially as evidence is …

The rate of skin aging, or that of tissue in general, is determined by a variable predominance
of tissue degeneration over tissue regeneration. This review discusses the role of oxidative …

Background High tumor mutational burden (TMB) is an emerging biomarker of sensitivity to
immune checkpoint inhibitors and has been shown to be more significantly associated with …

Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Pharmacotherapy is often severely hindered by issues related to poor drug selectivity,
including side effects, environmental toxicity, and the emergence of resistance. Lack of …

Human skin is repeatedly exposed to UVR that influences the function and survival of many
cell types and is regarded as the main causative factor in the induction of skin cancer. It has …

Solar radiation, especially ultraviolet (UV) light, is a major hazard for most skin‐related
cancers. The growing needs for wearable health monitoring systems call for a high …

Unlike most tumor suppressor genes, the most common genetic alterations in tumor protein
p53 (TP53) are missense mutations,. Mutant p53 protein is often abundantly expressed in …

The basal cell nevus syndrome (BCNS) is characterized by developmental abnormalities
and by the postnatal occurrence of cancers, especially basal cell carcinomas (BCCs), the …

The field of photopharmacology uses molecular photoswitches to establish control over the
action of bioactive molecules. It aims to reduce systemic drug toxicity and the emergence of …