Gene essentiality is a founding concept of genetics with important implications in both
fundamental and applied research. Multiple screens have been performed over the years in …

Essential genes are critical for the growth and survival of any organism. The machine
learning approach complements the experimental methods to minimize the resources …

Streptococcus gallolyticus is a non-motile, gram-positive bacterium that causes infective
endocarditis. S. gallolyticus has developed resistance to existing antibiotics, and no vaccine …

Identifying essential proteins plays an important role in disease study, drug design, and
understanding the minimal requirement for cellular life. Computational methods for essential …

Essential genes contain key information of genomes that could be the key to a
comprehensive understanding of life and evolution. Because of their importance, studies of …

Bacterial cells are widely used to produce value-added products due to their versatility, ease
of manipulation, and the abundance of genome engineering tools. However, the efficiency of …

Essential genes are thought to be critical for the survival of the organisms under certain
circumstances and the natural selection acting on essential genes is expected to be stricter …

Cyanobacteria are prokaryotic organisms that capture energy from sunlight using oxygenic
photosynthesis and transform CO2 into products of interest such as fatty acids …

Streptococcus gallolyticus (Sg) is a non-motile, gram-positive bacterium that causes infective
endocarditis (inflammation of the heart lining). Because Sg has gained resistance to existing …

ABSTRACT Objectives Salmonella Typhi biofilm condition is showing as a major public
health problem due to the development of antibiotic resistance and less available druggable …