[HTML][HTML] Sirtuins as Key Regulators in Pancreatic Cancer: Insights into Signaling Mechanisms and Therapeutic Implications

S Chouhan, A Kumar, N Muhammad, D Usmani… - Cancers, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) stands as one of the most lethal cancers,
marked by rapid progression, pronounced chemoresistance, and a complex network of …

[HTML][HTML] Molecular Sentinels: Unveiling the Role of Sirtuins in Prostate Cancer Progression

S Chouhan, N Muhammad, D Usmani… - International Journal of …, 2024 - mdpi.com
Prostate cancer (PCa) remains a critical global health challenge, with high mortality rates
and significant heterogeneity, particularly in advanced stages. While early-stage PCa is …

[HTML][HTML] Targeting PI3K signaling in Lung Cancer: advances, challenges and therapeutic opportunities

B Zhang, PC Leung, WCS Cho… - Journal of …, 2025 - … -medicine.biomedcentral.com
Lung cancer remains the leading cause of cancer-related mortality globally, necessitating
the continual exploration of novel therapeutic targets. The phosphoinositide 3-kinase (PI3K) …