Biology of claudins
Claudins are a family of tight junction membrane proteins that regulate paracellular
permeability of epithelia, likely by forming the lining of the paracellular pore. Claudins are …
permeability of epithelia, likely by forming the lining of the paracellular pore. Claudins are …
Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1
The extraordinarily thin alveolar type 1 (AT1) cell constitutes nearly the entire gas exchange
surface and allows passive diffusion of oxygen into the blood stream. Despite such an …
surface and allows passive diffusion of oxygen into the blood stream. Despite such an …
[HTML][HTML] The membrane proteome of the mouse lens fiber cell
Purpose Fiber cells of the ocular lens are bounded by a highly specialized plasma
membrane. Despite the pivotal role that membrane proteins play in the physiology and …
membrane. Despite the pivotal role that membrane proteins play in the physiology and …
Gene knockout inference with variational graph autoencoder learning single-cell gene regulatory networks
In this paper, we introduce Gene Knockout Inference (GenKI), a virtual knockout (KO) tool for
gene function prediction using single-cell RNA sequencing (scRNA-seq) data in the …
gene function prediction using single-cell RNA sequencing (scRNA-seq) data in the …
Zebrafish TMEM47 is an effective blocker of IFN production during RNA and DNA virus infection
LF Lu, ZC Li, C Zhang, DD Chen, KJ Han… - Journal of …, 2023 - Am Soc Microbiol
Mitochondrial antiviral signaling protein (MAVS) and stimulator of interferon (IFN) genes
(STING) are crucial factors of IFN induction in RNA and DNA viral infections. However …
(STING) are crucial factors of IFN induction in RNA and DNA viral infections. However …
Claudins reign: The claudin/EMP/PMP22/γ channel protein family in C. elegans
JS Simske - Tissue barriers, 2013 - Taylor & Francis
The claudin family of integral membrane proteins was identified as the major protein
component of the tight junctions in all vertebrates. Since their identification, claudins, and …
component of the tight junctions in all vertebrates. Since their identification, claudins, and …
Transcriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptide
B Maino, MT Ciotti, P Calissano… - International journal of …, 2014 - mdpi.com
Apoptosis triggered by exogenous or endogenous stimuli is a crucial phenomenon to
determine the fate of neurons, both in physiological and in pathological conditions. Our …
determine the fate of neurons, both in physiological and in pathological conditions. Our …
Vertebrate Claudin/PMP22/EMP22/MP20 family protein TMEM47 regulates epithelial cell junction maturation and morphogenesis
Y Dong, JS Simske - Developmental Dynamics, 2016 - Wiley Online Library
Background: TMEM47 is the vertebrate orthologue of C. elegans VAB‐9, a tetraspan
adherens junction protein in the PMP22/EMP/Claudin family of proteins. VAB‐9 regulates …
adherens junction protein in the PMP22/EMP/Claudin family of proteins. VAB‐9 regulates …
Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation
The Tmhs gene codes for a tetraspan transmembrane protein that is expressed in hair cell
stereocilia. We previously showed that a spontaneous missense mutation of Tmhs underlies …
stereocilia. We previously showed that a spontaneous missense mutation of Tmhs underlies …
Claudin Family Proteins in Caenorhabditis elegans
In the last decade, the claudin family of integral membrane proteins has been identified as
the major protein component of the tight junctions in all vertebrates. The claudin superfamily …
the major protein component of the tight junctions in all vertebrates. The claudin superfamily …