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Hepatic inflammatory responses in liver fibrosis
Chronic liver diseases such as nonalcoholic fatty liver disease (NAFLD) or viral hepatitis are
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …
Alcohol-associated liver disease
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …
and comprises a spectrum of several different disorders, including simple steatosis …
The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …
leading causes of chronic liver disease worldwide. NAFLD and ALD share …
Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models
D Feng, X **_the_hepatic_immune_landscape_identifies.14.aspx" data-clk="hl=iw&sa=T&ct=res&cd=4&d=13023634978699666931&ei=CwvAZ9KBCJuoieoPi-LziAc" data-clk-atid="8-W-zQI_vbQJ" target="_blank">Map** the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression
Conclusions: Loss of hepatocytes and increased ductular reaction are tightly associated with
monocyte-derived macrophage accumulation and represent the most prominent common …
monocyte-derived macrophage accumulation and represent the most prominent common …
Reactive oxygen species regulation by NCF1 governs ferroptosis susceptibility of Kupffer cells to MASH
J Zhang, Y Wang, M Fan, Y Guan, W Zhang, F Huang… - Cell Metabolism, 2024 - cell.com
Impaired self-renewal of Kupffer cells (KCs) leads to inflammation in metabolic dysfunction-
associated steatohepatitis (MASH). Here, we identify neutrophil cytosolic factor 1 (NCF1) as …
associated steatohepatitis (MASH). Here, we identify neutrophil cytosolic factor 1 (NCF1) as …
[HTML][HTML] Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death, and lipolysis
Background & Aims Binge drinking in patients with metabolic syndrome accelerates the
development of alcohol-associated liver disease. However, the underlying mechanisms …
development of alcohol-associated liver disease. However, the underlying mechanisms …
[HTML][HTML] The role of neutrophils in alcohol-related hepatitis
Alcohol-related liver disease is a major cause of liver disease-associated mortality, with
inpatient care being a major contributor to its clinical and economic burden. Alcohol-related …
inpatient care being a major contributor to its clinical and economic burden. Alcohol-related …
Effect of natural polysaccharides on alcoholic liver disease: A review
S Li, X Zhou, R Chen, Q Zhang, Y Sun… - International Journal of …, 2023 - Elsevier
In this study, we systematically collected relevant literature in the past five years on the
intervention of natural polysaccharides in alcoholic liver disease (ALD) and reviewed the …
intervention of natural polysaccharides in alcoholic liver disease (ALD) and reviewed the …
Alcohol-associated liver cancer
Heavy alcohol intake induces a wide spectrum of liver diseases ranging from steatosis,
steatohepatitis, cirrhosis, and HCC. Although alcohol consumption is a well-known risk …
steatohepatitis, cirrhosis, and HCC. Although alcohol consumption is a well-known risk …