Mobility of plasmids
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …
They code for genes involved in many aspects of microbial biology, including detoxication …
Evolutionary ecology of prokaryotic immune mechanisms
Bacteria have a range of distinct immune strategies that provide protection against
bacteriophage (phage) infections. While much has been learned about the mechanism of …
bacteriophage (phage) infections. While much has been learned about the mechanism of …
PhiSpy: a novel algorithm for finding prophages in bacterial genomes that combines similarity- and composition-based strategies
Prophages are phages in lysogeny that are integrated into, and replicated as part of, the
host bacterial genome. These mobile elements can have tremendous impact on their …
host bacterial genome. These mobile elements can have tremendous impact on their …
Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics
Abstract Group A Streptococcus (GAS; Streptococcus pyogenes) is a bacterial pathogen for
which a commercial vaccine for humans is not available. Employing the advantages of high …
which a commercial vaccine for humans is not available. Employing the advantages of high …
Conjugative and mobilizable genomic islands in bacteria: evolution and diversity
Horizontal transfer of genomic islands (GEIs), that is, chromosomal regions encoding
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …
Antibiotic resistance genes in the bacteriophage DNA fraction of environmental samples
M Colomer-Lluch, J Jofre, M Muniesa - PloS one, 2011 - journals.plos.org
Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic
usage, greater mobility of the population, and industrialization. Many antibiotic resistance …
usage, greater mobility of the population, and industrialization. Many antibiotic resistance …
[HTML][HTML] Streptococcus pneumoniae: virulence factors and variation
Streptococcus pneumoniae is a major pathogen of humans, causing diseases such as
pneumonia and meningitis. The organism produces several virulence factors that are …
pneumonia and meningitis. The organism produces several virulence factors that are …
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A
Streptococcus to unravel the nature and timing of molecular events contributing to the …
Streptococcus to unravel the nature and timing of molecular events contributing to the …
The current state of poststreptococcal glomerulonephritis
B Rodriguez-Iturbe, JM Musser - Journal of the American Society …, 2008 - journals.lww.com
Poststreptococcal glomerulonephritis is one of the oldest recognized renal diseases. In the
past three decades, significant changes have occurred in its epidemiology, in new insight …
past three decades, significant changes have occurred in its epidemiology, in new insight …
CRISPR-Cas in Streptococcus pyogenes
The discovery and characterization of the prokaryotic CRISPR-Cas immune system has led
to a revolution in genome editing and engineering technologies. Despite the fact that most …
to a revolution in genome editing and engineering technologies. Despite the fact that most …