Multiple myeloma (MM) is a dyscrasia of plasma cells (PCs) characterized by abnormal
immunoglobulin (Ig) production. The disease remains incurable due to a multitude of …

Accumulation of somatic hematopoietic stem cell mutations with aging has been revealed by
the recent genome-wide analysis. Clonal expansion, known as clonal hematopoiesis of …

Clonal hematopoiesis of indeterminate potential (CHIP) refers to the phenomenon where a
hematopoietic stem cell acquires fitness-increasing mutation (s), resulting in its clonal …

Simple Summary Patients suffering from multiple myeloma receive many lines of treatment
including chimeric antigen receptor T cell (CART) therapy. Myeloma patients may develop …

Somatic mutations of hematopoietic cells in the peripheral blood of normal individuals refer
to clonal hematopoiesis of indeterminate potential (CHIP), which is associated with a 0.5 …

Perivascular epithelioid cell tumors (PEComa) are a large family of mesenchymal
neoplasms, with variable clinical course. Evidence regarding treatment of advanced …

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition
characterized by the presence of low levels of a monoclonal protein in the serum and a low …

Accurate and precise diagnosis made the medicine the hallmark of evidence-based
medicine. While attaining absolute patient satisfaction may seem impossible in the aspect of …

Immunoglobulin light-chain (AL) amyloidosis is characterized by the deposition of misfolded
monoclonal free light chains, with cardiac complications accounting for patient mortality …

In this issue of the Red Journal, Zhang et al. 1 investigated the relationship between bone
marrow volume and the risk of cytopenias in 125 patients with multiple myeloma (MM) …