Adaptive laboratory evolution of ale and lager yeasts for improved brewing efficiency and beer quality

B Gibson, M Dahabieh, K Krogerus… - Annual review of …, 2020 - annualreviews.org
Yeasts directly impact the efficiency of brewery fermentations as well as the character of the
beers produced. In recent years, there has been renewed interest in yeast selection and …

Improved betulinic acid biosynthesis using synthetic yeast chromosome recombination and semi-automated rapid LC-MS screening

GOF Gowers, SM Chee, D Bell, L Suckling… - Nature …, 2020 - nature.com
Synthetic biology, genome engineering and directed evolution offer innumerable tools to
expedite engineering of strains for optimising biosynthetic pathways. One of the most radical …

Simulations reveal challenges to artificial community selection and possible strategies for success

L ** the role of AcrAB-TolC efflux pumps in the evolution of antibiotic resistance reveals near-MIC treatments facilitate resistance acquisition
AM Langevin, I El Meouche, MJ Dunlop - Msphere, 2020 - journals.asm.org
Antibiotic resistance has become a major public health concern as bacteria evolve to evade
drugs, leading to recurring infections and a decrease in antibiotic efficacy. Systematic efforts …

Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal Gene Transfer and Suggests Adaptive and Neutral Effects

S Slomka, I Françoise, G Hornung, O Asraf… - Genetics, 2020 - academic.oup.com
Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal
Gene Transfer and Suggests Adaptive and Neutral Effects | Genetics | Oxford Academic Skip to …

Reconfiguring the challenge of biological complexity as a resource for biodesign

EA Szymanski, J Henriksen - Msphere, 2022 - journals.asm.org
Biological complexity is widely seen as the central, intractable challenge of engineering
biology. Yet this challenge has been constructed through the field's dominant metaphors …

Transcriptional rewiring, adaptation, and the role of gene duplication in the metabolism of ethanol of Saccharomyces cerevisiae

B Sabater-Muñoz, F Mattenberger, MA Fares, C Toft - MSystems, 2020 - journals.asm.org
Ethanol is the main by-product of yeast sugar fermentation that affects microbial growth
parameters, being considered a dual molecule, a nutrient and a stressor. Previous works …