Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

Oxidative stress is one of the important factors in the development of alcoholic liver disease.
The production of reactive oxygen species and other free radicals is an important feature of …

Natural products (NPs) have consistently played a pivotal role in pharmaceutical research,
exerting profound impacts on the treatment of human diseases. A significant proportion of …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which is mainly
caused by the damage of the structure and function of the central nervous system. At …

Cancer is identified as second leading causes of death and imposes a significant
psychological and economic burden on societies. Due to its high prevalence, and a main …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
As a result, pharmaceutical and non-pharmaceutical interventions modifying risk factors for …

Background: Peyronie's disease (PD) is a chronic inflammatory condition affecting adult
males, involving the tunica albuginea of the corpora cavernosa of the penis. PD is frequently …

Background Neurochemical dysregulations resulting from N-methyl-D-aspartate
hypofunction (NMDA), are exacerbated by neuroimmune and oxidative stress and are …

Background Despite centuries of traditional use of silymarin for hepatoprotection, current
randomized controlled trial (RCT) studies on the effectiveness of silymarin in managing …

Silymarin, a bioflavonoid derived from the Silybum marianum plant, was discovered in 1960.
It contains C 25 and has been extensively used as a therapeutic agent against liver-related …