Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects

J Yin, J Zhan, Q Hu, S Huang, W Lin - Chemical Society Reviews, 2023 - pubs.rsc.org
Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

Small-molecule fluorescence-based probes for interrogating major organ diseases

HH Han, H Tian, Y Zang, AC Sedgwick, J Li… - Chemical Society …, 2021 - pubs.rsc.org
Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …

A polarity‐sensitive ratiometric fluorescence probe for monitoring changes in lipid droplets and nucleus during ferroptosis

KN Wang, LY Liu, D Mao, S Xu, CP Tan… - Angewandte Chemie …, 2021 - Wiley Online Library
Ferroptosis regulates cell death through reactive oxygen species (ROS)‐associated lipid
peroxide accumulation, which is expected to affect the structure and polarity of lipid droplets …

Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

[HTML][HTML] Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway

R **e, W Zhao, S Lowe, R Bentley, G Hu, H Mei… - Free Radical Biology …, 2022 - Elsevier
Background Epilepsy is one of the most common neurological disorders in childhood.
However, classical antiepileptic drugs are linked with drug toxicity and cognitive function …

[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy

W Liu, X Cui, Y Zhong, R Ma, B Liu, Y **a - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO, Viscosity, and Polarity and Its Application in Ferroptosis and Cancer Models

L Fan, Q Yang, Q Zan, K Zhao, W Lu, X Wang… - Analytical …, 2023 - ACS Publications
Intracellular peroxynitrite anions (ONOO–) and microenvironments (such as viscosity and
polarity) play an important role in maintaining redox homeostasis, regulating diffusion …

Super-resolution imaging of mitochondrial HClO during cell ferroptosis using a near-infrared fluorescent probe

H Fang, Y Chen, S Geng, S Yao, Z Guo… - Analytical …, 2022 - ACS Publications
Ferroptosis is of great importance in physiological and pathological processes, which is
associated with various inflammation-related diseases, cardiovascular diseases, and even …

Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease

L Gao, W Wang, X Wang, F Yang, L **e… - Chemical Society …, 2021 - pubs.rsc.org
Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …